Lecture 38-39- GI Secretions Flashcards

1
Q

Primary mediator of HCl production

A

Acetocholine

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2
Q

What is acetylcholine’s role in digestion?

A

Stimulate gastrin release which stimulates HCl prduction

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3
Q

What enteric cells produce histamine

A

ECL

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4
Q

Is stomach pH higher or lower whne fasting?

A

Lower

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5
Q

What is triggered by acidic chyme entering the duodenum?

A

Secretin and CCK release

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6
Q

Where is HCl and bicarbonate released in relation to a parietal cell

A

HCl is released on the lumenal side
Bicarbonate is released into the blood stream

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7
Q

What pH change occurs in the blood after eating

A

Alkalization due to bicarbonate

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8
Q

Why is pepsinogen stored in chief cells as granules

A

To prevent cell destruction

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9
Q

What stimulates release of pancreatic secretions

A

Ach, secretin, and CCK

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10
Q

What animal lacks a gallbladder

A

Horses

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11
Q

What stimulates gallbladder contractions

A

CCK

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12
Q

What chemical is the precursor for bile

A

Cholesterol

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13
Q

What is a bile salt

A

A bile acid bound to an amino acid

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14
Q

Which two amino acids can conjugate a bile acid

A

GLycine and taurine

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15
Q

where is most bile reabsorbed

A

the ileum

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16
Q

What does it mean when bile acids increase dramatically after a meal

A

Liver shunt

17
Q

Where are bile acid micelles formed

A

THe lumen of the intestines