Lecture 38-39- GI Secretions Flashcards
Primary mediator of HCl production
Acetocholine
What is acetylcholine’s role in digestion?
Stimulate gastrin release which stimulates HCl prduction
What enteric cells produce histamine
ECL
Is stomach pH higher or lower whne fasting?
Lower
What is triggered by acidic chyme entering the duodenum?
Secretin and CCK release
Where is HCl and bicarbonate released in relation to a parietal cell
HCl is released on the lumenal side
Bicarbonate is released into the blood stream
What pH change occurs in the blood after eating
Alkalization due to bicarbonate
Why is pepsinogen stored in chief cells as granules
To prevent cell destruction
What stimulates release of pancreatic secretions
Ach, secretin, and CCK
What animal lacks a gallbladder
Horses
What stimulates gallbladder contractions
CCK
What chemical is the precursor for bile
Cholesterol
What is a bile salt
A bile acid bound to an amino acid
Which two amino acids can conjugate a bile acid
GLycine and taurine
where is most bile reabsorbed
the ileum