Lecture 3 Flashcards
What is the plasma membrane made of?
lipid bylayer
What is the plasma membrane?
all around the outside of the cell
What is the cytoplasm?
everything inside the plasma membrane
What is the cytosol?
Kelly stuff between the organelles
What are organelles?
the structures inside a cell
What is the nucleus?
the brain of the cell
What is chromatin?
DNA and associated proteins
What does the rough endoplasmic reticulum do?
protein synthesis
What does the smooth endoplasmic reticulum do?
lipid synthesis
What is the difference between rough and smooth endoplasmic reticulum?
rough EPR has ribosomes on it
What does the Golgi apparatus do?
helps transporting things from the endoplasmic reticulum
What is a Golgi vesicle?
a vessel that has broken off of the Golgi apparatus to transport something
What is a peroxisome?
a membrane bound organelle that contains mostly enzymes; performs lipid metabolism and chemical detoxification
What is a lysosome?
contains enzymes that break down and digest unneeded cellular components like a damaged organelle
What is microfilament?
cytoskeleton mostly in muscular cells; helps with muscle contraction
What is a centrosome?
the motor of cell division
What is the mitochondria?
the powerhouse of the cell
What is a ribosome?
the site of protein synthesis
What are the four types of tissue?
nervous, muscle, epithelial, connective
What is the first characteristic of epithelial tissue?
highly cellular, minimal extracellular matrix
What is the second characteristic of epithelial tissue?
polarity, tissue has an apical and basal surface
What is the third characteristic of epithelial tissue?
attachment to a basement membrane
What is the fourth characteristic of epithelial tissue?
avascular; blood vessels are found in underlying connective tissue
What is the fifth characteristic of epithelial tissue?
regeneration; high regenerative capacity
What is the basement membrane?
in-between two types of tissue; eg. epithelial tissue and connective tissue like the skin
What is the apical surface?
the top of epithelial tissue; outside of the skin or the very inside of an organ
What is the basal surface?
the bottom of the epithelial tissue
What are the functions of epithelial tissue?
physical protection, selective permeability, secretion
What are the three types of intercellular junctions?
tight junctions, gap junctions, anchoring junctions
What do tight junctions do?
don’t let anything through from other cells
What do gap junctions do?
allows small molecules and ions between the cytoplasm of adjacent cells; allow electrical and metabolic coupling of adjacent cells
What do anchoring junctions do?
holds the cell to something
What type of junctions are desmosomes?
anchoring
What type of junctions are adherens?
anchoring
What type of junctions are hemidesmosomes?
anchoring
What do hemidesmosomes do?
makes the cells not pull apart from the basement membrane
What do desmosomes do?
keep cells together
What do adherens do?
can do what hemidesmosomes or desmosomes do but they have actin in them
What are the types of simple epithelia?
squamous, cuboidal, columnar
What are the types of stratified epithelia?
squamous, cuboidal, columnar
What is the odd one out of epithelia?
pseudostratified
What shape are squamous epithelia cells?
flat
What shape are cuboidal epithelia cells?
cube like
What shape are columnar epithelia cells?
column/cylindrical like
What do pseudostratified epithelia cells look like?
looks like it’s stratified but it’s not; nucleus in different places
What are the functions of simple squamous epithelium?
diffusion and filtration
Where are simple squamous epithelium located?
lung air sacs (alveoli), lining of blood vessels, serous membranes
What are the functions of simple cuboidal epithelium?
absorption and secretion
Where are simple cuboidal epithelium located?
kidney tubules, glands
What are the functions of simple columnar epithelium?
absorption, secretion, movement (if ciliated)
Where are simple columnar epithelium located?
lining of stomach, small intestine, and large intestine (non-ciliated); lining of uterine tubes (ciliated)
What are the functions of pseudostratified columnar epithelium?
protection, movement (if ciliated)
Where are pseudostratified columnar epithelium located?
lining of respiratory tract
What are the functions of stratified squamous epithelium?
protection
Where are stratified squamous epithelium cells located?
epidermis of skin, lining of oral cavity, pharynx, esophagus, anus, vagina
What are the functions of transitional epithelium?
distention and relaxation of urinary structures
Where is transitional epithelium located?
lining of ureters, bladder, and erethra
What is the only system that transitional epithelium are found in?
urinary system
What is cilia used for?
moves stuff around the cell
What are the two types of glandular epithelium?
exocrine and endocrine
What are exocrine glands?
secrete products onto an epithelial surface
What are the two types of glands that are mostly exocrine
simple alveolar (acinar) and simple branched alveolar (sebaceous/oil glands)
What are endocrine glands?
secrete hormones; ductless, secrete products into interstitial fluid and bloodstream, form the endocrine system
What are the more endocrine glandular epithelium?
simple tubular, simple coiled tubular, simple branched tubular
Where are simple tubular glands found?
intestinal glands
Where are simple oiled tubular glands found?
merocrine sweat glands
Where are simple branched tubular glands found?
gastric glands and mucous glands of esophagus, tongue, duodenum
What are the three types of secretion?
merocrine, apocrine, holocrine
What is merocrine secretion?
secretion through the vesicle; tears and sweat
What is apocrine secretion?
part of the cell pinches off and that part is the secretion; cell stays alive; breast milk
What is holocrine secretion?
mature cell dies and becomes secretory product; explodes; digestion
What are the functions of connective tissue?
physical protection, support and structural framework, binding of structures, storage, transport (blood), immune protection
What are the three types of tissues that come from mesenchyme?
connective tissue proper, supporting connective tissue, fluid connective tissue
What are the types of connective tissue proper?
loose connective tissue, dense connective tissue
What are the three types of loose connective tissue?
areolar, adipose, reticular
What are the three types of dense connective tissue?
regular, irregular, elastic
What are the types of supporting connective tissue?
cartilage (semisolid matrix) and bone (solid matrix)
What are the three types of cartilage?
hyaline, fibrocartilage, elastic
What are the two types of bone?
compact and spongy
What is fluid connective tissue?
blood and lymph
What is a blast?
immature cell
What is a cyte?
mature cell
What is a plast?
dead/dying cell
What does areolar tissue do?
surrounds and protects organs, loosely binds epithelia to deeper tissues
Where is areolar tissue found?
subcutaneous tissue, dermis of skin
What is the structure of areolar tissue?
fibroblasts, collagen and elastic fibers, abundant ground substance
What is the function of adipose tissue?
stores energy, protects, cushions, insulates
What is the structure of adipose tissue?
adipocytes in a loose extracellular matrix
Where is adipose tissue located?
surround organs, subcutaneous tissue; fat
What is the function of reticular tissue?
provides supportive framework
What is the structure of reticular tissue?
white blood cells and fibroblasts, reticular fibers, ground substance
Where is reticular tissue found?
lymph nodes, spleen, bone marrow
What is the structure of dense regular connective tissue?
dense, parallel collagen fibers, fibroblasts, sparse ground substance
What is the function of dense regular connective tissue?
resists stress in one direction
Where is dense regular connective tissue found?
tendons, ligaments
What is the structure of dense irregular connective tissue?
collagen fibers randomly arranged, fibroblasts, sparse ground substance
What is the function of dense irregular connective tissue?
resists stresses in all directions
Where is dense irregular connective tissue found?
dermis of skin, organ capsules
What is the structure of dense elastic tissue?
dense elastic fibers, fibroblasts
What is the function of dense elastic tissue?
allows stretching
Where is dense elastic tissue found?
walls of large arteries and airways
What is the structure of cartilage?
semisolid matrix containing chondrocytes
What is the function of cartilage?
provides support and flexibility, absorbs compression
Where is cartilage found?
ends of long bones, trachea, intervertebral discs, external ear
What is the structure of bone?
calcified, solid matrix containing osteocytes
What is the function of bone?
protection, support, movement (with muscular system), stores calcium
Are red or white blood cells bigger?
red blood cells
What is the structure of fluid connective tissue?
contains red blood cells, white blood cells, and platelets; water-based ground substance called plasma
What is the function of fluid connective tissue?
transports gases (oxygen and carbon dioxide), nutrients, and waste, participates in immune response and blood clotting
Where is fluid connective tissue found?
blood vessels and heart
What is scurvy?
nutritional disorder caused by vitamin C deficiency
What are the symptoms of scurvy?
weakening of gums, teeth, bones, and internal mucosa; wounds and fractures don’t heal well
Why does scurvy happen?
normal collagen fibers cannot form
What is Marfan syndrome?
genetic disease where there are abnormalities in fibrillar, a protein that builds elastic fibers
What happens to people with Marfan syndrome?
tall and thin with long legs, arms, fingers, and toes; typically die by age 50 because of heart weakness
What happens when you have Marfan syndrome?
causes skeletal, cardio, vision, and connective tissue abnormalities
How is gangrene formed?
caused by lack of blood flow that may be due to mechanical injury, bacterial infection, or diabetes
What does gangrene commonly affect?
limbs, fingers, toes