Lecture 25 - Clinical 2, Cerebellar Disease

Question 1

Afferents from?

Answer 1

spinal cord, vestibular nuclei via ION, pontine nuclie

Question 2

Efferents to?

Answer 2

upper motor neurons via thalamus, lower motor neurons via vestibular nuclei, reticular formation and red nucleus

Question 3

Truncal ataxia?

Answer 3

unsteady, heel-toe (or heels if mid-line cerebellum)

Question 4

Limb ataxia?

Answer 4

clumbsiness, intention tremor; ipsilateral to lesion and indicative of hemispherical disease

Question 5

Dysarthia?

Answer 5

loss of articulation, slurred staccato speech, NOT dysphasia

Question 6

Associated symptoms?

Answer 6

abnormal eye movements (nyastagmus), vertigo, nausea; all these not necessary

Question 7

Causes?

Answer 7

congenital, MS, autoimmune, infection, hypoxia, toxins