Lecture 18 Folate - MC

Question 1

What condition was the discovery of folate primarily aimed at curing?
A) Scurvy
B) Pellagra
C) Megaloblastic anemia
D) Beriberi

Answer 1

C

Question 2

Folate is made up of which three components?
A) Ascorbic acid, citric acid, and glutamic acid
B) 2-amino-4-hydroxypteridine, PABA, and glutamic acid
C) Riboflavin, niacin, and thiamine
D) Pyridoxine, cobalamin, and pantothenic acid

Answer 2

B

Question 3

What role does the enzyme dihydrofolate reductase play in folate metabolism?
A) It breaks down folate into its constituent parts.
B) It converts dihydrofolate into tetrahydrofolate.
C) It synthesizes folate from simpler organic molecules.
D) It removes glutamates from folate molecules.

Answer 3

B

Question 4

*What is the significance of the number of glutamates in naturally occurring folate in foods?
A) They determine the vitamin’s solubility in water.
B) They affect how quickly the vitamin is absorbed in the intestine.
C) They need to be reduced to a single glutamate for absorption.
D) They indicate the amount of energy the body can derive from folate.

Answer 4

C

Question 5

*What has been a significant public health outcome of food fortification with folic acid?
A) Reduction in the incidence of megaloblastic anemia.
B) Decrease in the rate of neural-tube defects such as spina bifida.
C) Increase in the absorption rates of vitamin B12.
D) Decrease in the rates of vitamin C deficiency.

Answer 5

B