Lecture 18 - Ch 27 - Microbial Interactions with Humans Flashcards
Microorganisms usually found associated with human body tissue
normal microbial flora
The decrease or loss of virulence
attenuation
Organism causes disease by means of a toxin that inhibits host cell function or kills host cells
toxicity
Ability of a pathogen to grow in host tissue at densities that inhibit host function
Invasiveness
Proteins released from the pathogen cell as it grows
exotoxins
what are the 3 types of exotoxins?
Cytolytic toxins
AB toxins
Superantigen toxins
which type of toxins are responsible for cell lysis?
Type II - membrane disrupting toxins
which type of toxins use enzymatic activity?
Type III - A-B Toxins
What are type I toxins?
Superantigens
What is an example of a superantigen?
Toxic Shock Syndrome (from Staphylococcus aureus)
What is the name of the endotoxin?
lipopolysaccharide (LPS)
Where do endotoxins attach to a cell?
the membrane of Gram (-) bacteria