Lecture 17 - Ch 26 - Microbial Growth Control Flashcards
The killing or removal of all viable organisms within a growth medium
sterilization
Effectively limiting microbial growth
inhibition
The treatment of an object to make it safe to handle
decontamination
Directly targets the removal of all pathogens, not necessarily all microorganisms
disinfection
resistant cells that Can survive heat that would rapidly kill vegetative cells
endospores
Sterilization method where high temperatures denature macromolecules
heat sterilization
sealed device that uses steam under pressure
autoclave
the process of using precisely controlled heat to reduce the microbial load in heat-sensitive liquids
pasteurization
this sterilization method avoids the use of heat on sensitive liquids and gases
filtration
chemical control that causes an arrest in growth
bacteriostatic
chemical control that kills the bacteria and leaves the dead cell
bacteriocidal
chemical control that kills the bacteria and lyses the cell
bacteriolytic
the smallest amount of an agent needed to inhibit growth of a microorganism
minimum inhibitory concentration (MIC)
beta-lactams Inhibit enzymes that catalyze __________.
transpeptidation
which antiobiotics Inhibit enzymes that catalyze transpeptidation of PG
beta-lactams
which antibiotics inhibit enzymes that catalyze transglycocylation
glycopeptides
bind to membrane phospholipids and interfere with membrane function
polymyxin
prevents the binding of 50S ribosome to 30S.
aminoglycosides
what is an example of a glycopeptide?
vancomycin
what are examples of aminoglycosides?
gentamicin and kanamycin
Prevents binding of tRNA to 30S
tetracycline
prevents 50S function
macrolides
what are examples of macrolides
erythromycin, azithromycin, lincomycin
Bind to and inhibit DNA gyrase
fluoroquinolones
give an example of a fluoroquinolone
Cipro
which antibiotics target DNA synthesis
fluoroquinolones
Binds to and inhibits RNA polymerase
rifamycins
Which antibiotics treat TB?
rifampicin
________ target transcription?
rifampicins