Ch 9 - Virology Flashcards

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1
Q

genetic element that cannot replicate independently of a living (host) cell

A

Virus

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2
Q

extracellular form of a virus

A

virion

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3
Q

are most viral genomes circular or linear?

A

mostly linear

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4
Q

the protein shell that surrounds the genome of a virus particle

A

capsid

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5
Q

subunit of the capsid

A

capsomere

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6
Q

complete complex of nucleic acid and protein packaged in the virion

A

nucleocapsid

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7
Q

virus that contains additional layers around the nucleocapsid

A

enveloped virus

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8
Q

viruses lyse host cells after infection

A

virulent mode

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9
Q

viruses replicate their genomes in tandem with host genome and without killing host

A

temperate mode

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10
Q

state where most virus genes are not expressed and virus genome (prophage) is replicated in synchrony with host chromosome

A

lysogeny

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11
Q

a bacterium containing a prophage

A

lysogen

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12
Q

release of virions from host cell does not result in cell lysis

A

persistent infections

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13
Q

delay between infection by the virus and lytic events

A

latent infections

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14
Q

conversion of normal cell into tumor cell

A

transformation

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15
Q

two or more cells become one cell with many nuclei

A

cell fusion

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16
Q

give an example of a retrovirus (ssRNA)

A

HIV

17
Q

give an example of a hepadnavirus (dsDNA)

A

hepatitis B

18
Q

Attachment of the virus to a susceptible host cell

A

adsorption

19
Q

Entry of the virion or its nucleic acid

A

penetration

20
Q

what are the phases of viral replication?

A

1) attachment
2) entry
3) synthesis of nucleic acids & proteins
4) assembly of capsids
5) release (lysis)

21
Q

two phases of the latent period

A

eclipse and maturation

22
Q

number of virions released

A

burst size

23
Q

proteins necessary for replication of virus nucleic acid

A

early proteins

24
Q

proteins that make up the structural components

A

late proteins

25
Q

these viruses can undergo a stable genetic relationship within the host

A

temperate

26
Q

viruses that are parasitic on other viruses

A

defective viruses

27
Q

infectious RNA molecules that lack a protein coat

A

viroids

28
Q

infectious proteins whose extracellular form contains no nucleic acid

A

prions

29
Q

these infectious proteins infect the PrnP gene

A

prions