Ch 12 - Microbial Genomics

Question 1

determining the precise order of nucleotides in a DNA or RNA molecule

Answer 1

sequencing

Question 2

converting raw sequence data into a list of genes present in the genome

Answer 2

annotation

Question 3

Science that applies powerful computational tools to DNA and protein sequences

Answer 3

bioinformatics

Question 4

The entire complement of RNA produced under a given set of conditions

Answer 4

Transcriptome

Question 5

Small solid-state supports to which genes or portions of genes are fixed and arrayed spatially in a known pattern

Answer 5

microarrays

Question 6

Genome-wide study of the structure, function, and regulation of an organism’s proteins

Answer 6

proteomics

Question 7

related in sequence to an extent that implies common genetic ancestry

Answer 7

homologous

Question 8

groups of gene homologs

Answer 8

gene families

Question 9

genes within an organism whose similarity to one or more genes in the same organism is the result of gene duplication

Answer 9

paralogs

Question 10

genes found in one organism that are similar to those in another organism but differ because of speciation

Answer 10

orthologs

Question 11

The transfer of genetic information between organisms, as opposed to vertical inheritance from parental organism(s)

Answer 11

horizontal gene transfer

Question 12

fight with the host for resources

Answer 12

obligate parasites

Question 13

live inside a host without harming it

Answer 13

endosymbiotic parasites

Question 14

first dimension of electrophoresis separates proteins by _______

Answer 14

isoelectric differences

Question 15

second dimension of electrophoresis separates proteins by ______

Answer 15

size

Question 16

Region of bacterial chromosome of foreign origin that contains clustered genes for some extra property such as virulence or symbiosis

Answer 16

chromosomal islands

Question 17

chromosomal islands containing genes for virulence

Answer 17

pathogenicity islands