lecture 17 Flashcards
the glandar sturcture of the secretory function of the GI tract
mucous Gland , glandular pits(TUBULAR) , tubular glands, Acinar aveolar
the secretory function of the GI tube
digestive enzymes to be secreted and secretion of mucus from mucus gland provide lubrication and protection
single cell mucous gland
mucous cell( globlet cell) , it is found on the surface off the epithelium in the GI Tract, its function is to respond to irritation of the epithelium by the producing mucus, which acts as a protectant to the surface from excorination and digestion
Glandular Pits(tubular )
this represents invagination of the epithelium into the submucosa , in the small intestine this pits is called the cryptes of lieberkihn
Tubular Glands
In the stomach and upper duodenum
Acinar(alveolar)
found in the salivary glands, pancreas, and liver, provided secretion for digestion or emulsificatin of food, In the GI tract these acini feed into a system that empty into the allimentary tract. this are exocrine glands
Stimulation of the secretory Glands is by
presence of food, Autonomic nervous system, and hormones
the presence of food in the gi tract activates
the enteric nervous system of the gut wall, there is tactile sensation, chemical irritation, and distention of the gut
parasympathetic stimulation of gland
affects the rate of alimentary glandular secretion from the glands in the upper portion of the tract eg salivary gland, esophagus gastric glands, pancreas, brunner’s gland( duodenum). this is innervated by the by the glossopharyngeal and vagus nerve
sympathetic stimulation of the secretory glands
cause moderate secretion by local gland, also resulting in constriction of blood vessels that supply the gland
dual effect of sympathetic stimulation
sympathetic stimulation will cause increase in secretion, but if parasympathetic or hormonal stimulation is in effect, then it will reduce stimulation
Hormones and stimulation of secretory glands
it regulates the volume and character of the secretion
the hormone are release from the GI mucosa in response to the presence of food
hormones are then absorbed into the blood and carried to the gland that will release secretion.
1 step of secretion of organic substance
- materials needed for formation of secretion must diffuse or be actively transported by the blood in the capillaries into the base of the glandular cell via merocrine secretion
2 step of secretion of organic substance
mitochondria located in the glandular cells near its base uses oxidative energy to form ATP
3 step of secretion of organic substance
atp and appropriate substance provided by the nutrient is used to synthesize organic substance. this occurs in the ER and Golgi complex.
4th step of secretion of organic substance
the secretory material are transported through the tubules of the ER to the vesicle of the Golgi
5th step of secretion of organic substance
In the Golgi material are modified and discharged into the cytoplasm in from of secretory vesicle, which are stored at the apex of the cell until stimulated
——–stimulation causes water and salt to pass through the glandular cells
nervous stimulation