Lecture 10 Part 2 Flashcards

1
Q

what occurs when there is an AA deficiency

A
  • poor growth
  • reduced milk and egg production
  • anorexia
  • infertility
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2
Q

absorption of proteins and AAs during 1st 24 hours after birth

A
  • large proteins
  • immunoglobins from colostrum
  • these large particles wont be able to be digested after first 24 hours
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3
Q

absorption after 24 hours

A

proteins digested and absorbed as AAs and peptides

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4
Q

digestion of proteins

A
  • begins in gastric stomach
  • small intestine (pancreatic region) that gives products of free AA, dipeptides, and tripeptides
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5
Q

pepsinogen + HCL=

A

pepsin

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6
Q

what hydrolyzes peptide bonds between specific AAs

A

Pro carboxypeptidase–> carboxypeptidase

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7
Q

absorption of AAs and peptides

A
  • occurs in small intestine
  • free AAs absorbed by active transport systems
  • absorption rate vary
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8
Q

ruminant absorption of AAs and peptides

A

may also occur in rumen and omasum

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9
Q

where are dipeptides and tripeptides absorbed

A
  • into mucosal cells
  • hydrolyzed to FAA before entering circulation
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10
Q

what are AAs used for

A
  • tissue protein synthesis
  • synthesis of enzymes, hormones, other metabolites
  • transamination-AA biosynthesis
  • deamination and use of carbon skeleton for energy
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11
Q

tissue protein synthesis

A
  • occurs in every cell of body, hormonal control
  • takes place at ribosome
  • requires tRNA, rRNA, mRNA, DNA
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12
Q

tRNA

A

caries specific AA and base pairs with mRNA

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13
Q

rRNA

A

part of ribosome

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14
Q

mRNA

A

determines AA sequence of a protein
- codons of 3 nucleotides

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15
Q

DNA

A

genetic code

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16
Q

tissue protein degradation

A
  • breakdown of proteins
  • fate of AAs from protein degradation
17
Q

breakdown of proteins

A
  • requires proteases
  • breakdown to AAs
  • stimulated by glucocorticoids
18
Q

what are the fate of AAs from protein degradation

A
  • used in synthesis of protein
  • broken down to NH2 and carbon skeleton if body needs energy
19
Q

what are the 2 processes in AA breakdown

A
  • deamination
  • transamination
20
Q

deamination

A
  • NH2 removed—> ammonia
  • ammonia disposed thru urea cycle
  • C skeleton–> keto acid, or gluconeogenesis, or ketogenesis
21
Q

transamination

A
  • resynthesis of AA
  • transfer NH2 from AA–>keto acid—>NEAA
  • C skeleton—>keto acid, or gluconeogenesis, or ketogenesis
22
Q

what are strictly ketogenic

A

leucine and lysine

23
Q

why do some AAs have different fats

A

due to structural uniqueness

24
Q

urea cycle

A
  • excretion of excess N
  • occurs in kidney and liver
  • several complex steps
  • energy expending
25
Q

what are the different forms of N for different animals

A

fish= ammonia
birds, snakes, lizards= uric acid
terrestrial vertebrates and sharks= urea

26
Q

how is urea excreted and recyclized

A
  • excreted in urine
  • in ruminants, recycled thru salvia to help fuel microbes
27
Q

LAAs

A

limiting amino acids

28
Q

what are the pre ruminants similar too when it comes to AA requirements

A

nonruminants

29
Q

MCP

A

ruminally synthesized microbial protein

30
Q

what are unprotected AAs

A

degraded

31
Q

how do proteins vary

A

in degree of degradation
- RDP or DIP
- RUP or UIP

32
Q

RDP and DIP

A

ruminally degraded protein
degraded intake protein
- same thing/meaning

33
Q

RUP or UIP

A

ruminally degraded protein
undegraded intake protein
- same thing/meaning
- bypass protein

34
Q

how does protein degradation and AA and protein synthesis happen

A

by rumen microbes

35
Q

bacterial proteins

A
  • high quality
  • quantity limits