Lec 24 Flashcards

1
Q

air flow pathway

A

1- nasal cavity
2- pharynx
3- larynx
4- trachea
5- primary bronchi
6- many smaller bronchi
7- bronchioles
8- terminal bronchioles
9- alveoli
10- air Sachs

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2
Q

upper respiratory system is

A

nasal cavity to larynx

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3
Q

lower respiratory system

A

trachea to alveoli

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4
Q

function of respiratory system

A

1- gas exchange
2- homeostatic regulaton of Ph: CO2 effect
3- condiotioning inspired air: warming, add water vapour
4- protection
5- vocalization

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5
Q

External respiration

A

Exchange I: atmosphere to lung
Exchange II: lung t blood
Transport of gases in blood
Exchange III: blood to cells

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6
Q

Lung to blood tissue exchange and important factors

A

alveoli to exchange epithelium
– fix law
– very thin capillaries

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7
Q

inspiration

A

air moves into lungs

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8
Q

expiration

A

air move out of lungs

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9
Q

ventilation

A

moving respiratory medium over respiratory surface

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10
Q

Which lung is bigger

A

right lung is slightly bigger

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11
Q

Left pleural cavity function

A

stick lungs to rib cage

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12
Q

Muscle of inspiration in normal breathing

A

1- external intercostals
2- diaphragm

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13
Q

external intercostal movement in normal breathing

A

up and out

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14
Q

diaphragm movement in normal breathing

A

down

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15
Q

forceful inspiration, extra muscles

A

1- sternocleido-mastoids
2- Scalenes

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16
Q

forceful expiration, extra muscles

A

1- internal intercostals
2- abdominal muscles

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17
Q

Lung intrapleural fluid

A

parietal pleura vs visceral pleura

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18
Q

parietal pleura function

A

stick to thoracic cavity wall

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19
Q

visceral pleura function

A

surround elestic tissue of lung

20
Q

Intrapleural fluid

A

1-watery
2- cannot separte parietal/visceral

21
Q

when lungs collapsed

A

if air enter to intrapleural space

22
Q

pleural membrane

A

1- visceral pleura
2- fluid intrapleural space
3- parietal pleura

23
Q

pleural sac function

A

1- protect lung
2- lubricate membrane and slide against each other
3- stick lungs tightly to the thoracic wll
4- important for keeping the lungs inflated

24
Q

Main role of the aairways

A

1- filter out foreign
2- warm air to body temperature
3- add water vapour = maximize exchange

25
cartilage ring tissue
connective tissue can't vasoconstrict/vasodilate
26
primary bronchus divide -- more times to reach alveoli
22
27
bronchiole tissue
no connective tissue--are adjustable
28
bronchoconstriction
increase resistance lower air flow
29
bronchodilation
decrease resistance increase air flow
30
cystic fibrosis
lost watery layer
31
common cause of increased airway resistance
mucus build up
32
obstructive lung disease ---- airway resistance
increase
33
cross-sectional area of trachea
2.5 cm^2
34
cross-scetionaal area of bronchioles
5*10^3 cm^2
35
most of resistance to flow is in
trachea
36
reistance is very low in
bronchioles
37
bronchodilation
decreased resistance to air flow 1- paracrine response to **CO2** 2- SNS response Gs -- AC -- cAMP -- PKA
38
bronchoconstriction
increased resistance to air flow 1- paracrine response to **histamine released in an immune response** 2- PNS response Gq -- PLC -- IP3 -- IP3R -- Ca ion
39
alveolar and capillaries key important factors
1- high surface area 2- low distance 3- concentration gradient
40
Alveoli
1- bulk of lung tissue 2- each alveolus is made of one layer of epithelial cells
41
two type of alveolar epithelial cells
1- type I alveolar cells 2- type II alveolar cells
42
type I alveolar cell
-gas exchange -95% of alveolar surface
43
type II alveolar cell
make and secrete surfactant
44
surfactant type
watery, lipidy
45
surfactant caused lung to
inflate