Lec 10-11 Flashcards

1
Q

CNS

A

Brain/spinal cord

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2
Q

Brain protect by

A

Bones of cranium

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3
Q

Spinal cord protect by

A

Bones of vertebral column

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4
Q

Meninges

A

Tissue membrane
Stabilize and protect neural tissue
Lie between bones and brain/spinal cord

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5
Q

Meninges parts from out to in

A

1- Dura meter
2- Arachnoid membrane
3- Pia meter

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6
Q

Ventricles of brain

A

4 ventricles
-within ventricles CSF produce

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7
Q

Functions of CSF

A

1- Physical Protection
——keeps brain tissue buoyant(reduce pressure)
——absorbs shock

2- Chemical Protection
——delivering nutrients to the brain
——removing waste
——allow tightly regulated extracellular environment

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8
Q

CSF is produced in

A

Choroid Plexus of ventricles

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9
Q

Choroid plexus

A

-Meeting of capillaries and ependymal cells
-Plasma filtered into ventricles
-Ependymal cells selectively transport solutes, water flow by osmosis
-transport ions and nutrients from blood to cerebrospinal fluid

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10
Q

CSF composition

A

Similar chemical composition to plasma but
——very low protein content in CSF

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11
Q

CSF is absorbed from subarachnoid space into venous circulation by——

A

Arachnoid villi

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12
Q

Total volume of CSF in adult

A

150 ml
-rate of secretion and absorption is equal

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13
Q

Subarachnoid space

A

Filled with CSF

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14
Q

Tight junction

A

Prevent moving larger solutes between endothelial cells

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15
Q

Astrocyte foot processes

A

Secrete paracrine onto endothelial cells that promote tight junction formation

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16
Q

Blood-Brain-Barrier

A

Blood-brain is leaky without astrocytes
Tight junction are caused by paracrine which is produced by astrocyte

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17
Q

Metabolic needs of neural tissue

A

1- Oxygen:
——pass freely across BBB
2- Glucose:
——need transporters - trancellularly
——only replacement is ketone——emergency situations
——brain consumption is about 20% of body total amount
——hypoglycemia leads to confusion

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18
Q

Gray matter

A

Nucleus
Dendrite/synapses
Deep inside or peripheral in BRAIN

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19
Q

White matter

A

Tracts of myelinated axon fibers
Lots of myelin

20
Q

Dorsal root

A

Posterior sensory
Bringing information to brain
Dorsal=Sensory=Afferent

21
Q

Ventral root

A

Outgoing information from brain to body
Ventral=Motor=Efferent

22
Q

Spinal cord

A

White is peripheral
Gray central

23
Q

Ascending tract

A

Axons from Spinal cord to brain

24
Q

Descending tract

A

Axons from brain to spinal cord

25
Brain compartments
Forebrain Brainstem Cerebellum
26
Medulla
Network automatic function Ascending and descending tracts
27
Pons
-some neuron for respiration -Relay station for pathway
28
Midbrain
Network eye movement and hearing
29
12 cranial nerves
Main nerves that project directly to/from brain rather than spinal cord
30
Basal ganglia
Control of limb movement, eye movement, Smoothing the movements when you want Preventing movement when you don’t want
31
Loss of neurons in basal ganglia
Huntington disease Parkinson disease
32
Cerebral cortex
1- Frontal Lobe——think 2- Parietal Lobe——touch, smell, hear 3- Occipital Lobe ——vision 4- Temporal Lobe ——hearing
33
Only lobe that is two
Temporal lobe
34
Thalamus
Relay station: receive sensory and motor info
35
Hypothalamus
Homeostasis and behavior
36
Pituitary gland
1- anterior: secrete hormones 2- posterior: secrete neurohormone that are mad in hypothalamus
37
Pineal gland
Secrete melatonin and regulate sleep-wake cycle
38
Major homeostatic control center
Hypothalamus
39
Hypothalamus functions
1- maintain body temperature 2- control body osmolarity 3- influence cardiovascular control 4- secrete trophic hormones
40
Limbic system
1- cingulate gyrus 2- hippocampus —— memory 3- amygdala —— emotion
41
Cerebullum
Rate,range,force of movement Input: all senses Output: cortex via thalamus and spinal cord via brain stem
42
Broca’s area
Verbally responding
43
Wernicke’s area
Language understanding center
44
Damage to wernicke
Receptive aphasia Loss of understanding but expression without meaning
45
Damage to broca
Expressive Aphasia Understanding maintain but lose ability of expression