Lab Med 91-105 Flashcards
What can cause sick euthyroid syndrome?
Acute injury
caloric deprivation
psychiatric illness
What can GGT be used for?
Alcohol induced liver disease
Recent alcohol ingestion
Source of elevated ALP
What can hCG levels indicate?
Double every 2 days, maximize in 1st trimester = pregnancy
Doubles with twins
What can increase the levels of circulating transcortin?
Pregnancy
Estrogen therapy
What can lead to an increase in unconjugated bilirubin WITHOUT a rise in conjugated bilirubin?
Conjugation problems Hemolytic disorders, Gilbert's, Arias, Crigler-Najjar, Immaturity of the liver, Cirrhosis
What can lead to elevated cortisol levels?
Cushing's Pregnancy BC Alcoholism Stress Starvation
What can lead to reduced cortisol levels?
Addison’s
Chronic illness
Adrenogenital syndrome
What can lower measured bilirubin?
Hemolysis,
light,
sun-bathing
What can raise measured bilirubin?
Fasting
Gilbert’s disease
What causes acquired euthyroid hyperthyroxinemia? (7)
Pregnancy Newborns Liver disease Acute intermittent porphyria Estrogen-producing tumors Hydatidiform mole Lymphosarcoma
What causes elevated blood ammonia?
Reduced removal from portal blood,
shunting past the liver,
protein-rich meals
What causes genetic euthyroid hyperthyroxinemia?
Abnormal increases in TBG, albumin, or prealbubmin
What does aldosterone do? How is it regulated?
Increases reabsorption of Na and HCO3
Increase excretion of H+ and K+
What does cortisol do?
Proteolysis Lipolysis Gluconeogeniss Anti-inflammatory response Immunosuppression Redistribute fat BP control
What does partial thromboplastin time (PTT) assess?
Severe hepatic dysfunction, specifically function of the intrinsic blood coagulation cascade
