Lab Med 181-195 Flashcards

1
Q

What is seen in hallucinogen overdose?

A

Minimal; often just behavioral effects

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2
Q

What is seen in iron toxicity - stage 1?

A
vomiting, 
diarrhea, 
ab pain, 
metabolic aCIDosis, 
hypERglycemia
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3
Q

What is seen in lead poisoning?

A

Demyelination of nerve fibers –> peripheral neuropathy, encephalopathy, decreased IQ, developmental disturbances, hypochromic anemia with basophilic stippling

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4
Q

What is seen in marijuana overdose?

A

Anxiety and mild paranoia

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5
Q

What is seen in meperidine overdose?

A

Parkinson’s

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6
Q

What is seen in opioid toxicity? Treatment?

A

Coma
Reduced respiration
Pinpoint pupils

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7
Q

What is seen in organophosphate or carbamate overdose?

A

SLUD - salivation, lacrimation, urination, defecation

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8
Q

What is seen in PCP overdose? Treatment?

A

Combative behavior –> give tranquilizer

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9
Q

What is seen in TCA toxicity?

A

Cardiac arrest due to QT prolongation

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10
Q

What is serum ferritin?

A

Chief iron storage form in the body Very sensitive indicator of iron status

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11
Q

What is serum iron?

A

Iron bound to transferrin

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12
Q

What is sick euthyroid syndome?

A

Low T3 syndrome = results from T4 shunting to form rT3 due to non-thyroid illness
Free values remain normal

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13
Q

What is sickle cell disease?

A

Having two mutant B genes

Lower RBC lifespan

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14
Q

What is sirolimus?

A

Prophylactic of organ rejection in renal transplant

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15
Q

What is streptokinase?

A

A thrombolytic that non-covalently binds to plasminogen

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16
Q

What is seen in iron toxicity - stage 2?

A

hypOvolemia,
HoTN
metabolic aCIDosis

17
Q

What is seen in iron toxicity - stage 3?

A
Multiple organ failure
hepatic failure (fatal)
18
Q

What is seen in iron toxicity - stage 4?

A

Gastric scarring

pyloric obstruction

19
Q

Tx lead poisoning with ____

A

EDTA

20
Q

Opioid tox tx with ______

A

naloxone

21
Q

Tx organophosphate/carbamate OD with _____

A

Treat with atropine or pralidoxime