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Lab Medicine > Lab Med 61-75 > Flashcards

Lab Med 61-75 Flashcards

1
Q

What are the signs of sirolimus toxicity? (6)

A 
HypERcholesterolemia 
HypER tg
Renal dysfx 
Pneumocystis 
Carinii infection 
CMV infection
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2
Q

What are the signs of tacrolimus toxicity?

A 
"My New Hat and The Hallowed Cat"  
Mental status 
Nephrotoxic 
HypERkalemia 
Tremor 
Headache 
Changes in motor function
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3
Q

What are the signs of theophylline toxicity?

A 
"VAN HHATS"  
Vomiting 
Anion gap 
Nausea 
HypOkalemia/hypERglycemia 
Acidosis 
TachyC 
Seizures
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4
Q

What are the signs of valproic acid toxicity?

A

Hepatic toxicity

Acute encephalopahty

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5
Q

What are the signs of vancomycin toxicity?

A

Ototoxic

Nephrotoxic

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6
Q

What are the stages of ethylene glycol intoxication? 3 stages

A
  1. CNS depression (12 hours)
  2. Cardiotoxic (24 hours)
  3. Renal stage (72 hours)
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7
Q

What are the steps in the coagulation cascade?

A

Injury releases TF –> activates VII –> activates IX and X –> binds V –> prothrombin to thrombin (II) –> fibrinogen to fibrin –> XIII crosslinks –> clot

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8
Q

What are the steps in the intrinsic coag pathway (amplification)?

A

XII –> XI –> IX + VIII –> X

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9
Q

What are the symptoms of acetaminophen toxicity? 4 steps

A
  1. GI distress
  2. General well being
  3. Liver toxicity
  4. Recovery
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10
Q

What are the symptoms of Conn’s syndrome? 9 sx’s

A 
HTN 
Weakness 
Tetany 
Paraesthesia 
Polydipsia 
Polyuria 
HypERnatermia 
HypOkalemia 
Metabolic alkalosis
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11
Q

What are the symptoms of elevated cortisol? (12)

A 
Truncal obesity 
Moon face 
Buffalo hump 
Abdominal purple striae 
Muscle weakness 
Osteoporosis 
HTN 
Amenorrhea 
Mental disturbances 
Hirsutism 
Virilization 
DM
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12
Q

What are the symptoms of hyperthyroidism?

A

“SWEATTTIINGG” with increased DTRs

Sweating 
Weight loss 
Emotional liability 
Appetite increased 
Tremor/Tachy/Tiredness 
Intolerance to heat/Irregular menstruation 
Nervousness 
Goiter/GI
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13
Q

What are the symptoms of hypothyroidism?

A

“MOMM’S SO TIREDD”

Memory loss 
Obesity 
Malar flush/ Menorrhagia 
Slowness 
Skin and hair dryness 
Onset gradual 
Tiredness 
Intolerance to cold 
Raised BP 
Energy levels fall (low labido) 
Depression/Delayed relaxation of reflexes (🠗 DTR's)
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14
Q

What are the symptoms of low cortisol?

A

WANT MMy Purple HHHeart

Weight loss 
Abdominal pain 
Nausea 
Tiredness 
Mental disturbances/metabolic acidosis 
Pigmentation of skin/buccal mucosa 
HypO tension/glucose/Na+

Other:
HypERkalemia
Elevated SUN

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15
Q

What are the three types of iron overload?

A

Hemosiderosis
Hemochromatosis
Heriditary hemochromatosis

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16
Q

All three types of iron overload have high ______, _____, and _____.

A

Serum Fe
Ferritin
Transferrin saturation

17
Q

Sx’s of elevated cortisol - fluids/osmolar/pH

A

Reabsorb of Na and H2O
HypOkalemia
Metabolic alkalosis
Elevated SUN

Lab Medicine (23 decks)

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