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Lab Medicine > Lab Med 166-180 > Flashcards

Lab Med 166-180 Flashcards

1
Q

What is prostate-specific antigen? Where is it found?

A

Glycoprotein and serine protease

Serum

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2
Q

What is prostatic acid phosphatase? Where is it found?

A

A phosphatase

Serum

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3
Q

What is prothrombin time, and what is the normal value?

A

Time to convert prothrombin to thrombin

Normal 10 s

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4
Q

What is PT used to evaluate?

A

Evaluates VII dependent pathways (extrinsic)

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5
Q

What is PTT used to evalute? What drug therapy is monitored with PTT? What diseases is PTT used to screen for?

A

To evaluate XII dependent pathways (intrinsic)
To monitor heparin therapy
To screen for hemophillia A and B

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6
Q

What is reteplase?

A

A thrombolytic drug

Tissue plasminogen activator

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7
Q

What is S-trait?

A

Sickle cell trait
Having one mutant B gene
Clinically silent

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8
Q

What is SC disease?

A

Having both S-trait and C-trait = less severe sickle cell disease

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9
Q

What low values are seen clinically in anemia? (5)

A 
RBC 
Hgb 
Hct 
MCV (iron deficient) 
MCH
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10
Q

What is seen clinically in sickle cell disease?

A

Decreased:
RBCs
Hgb
Hct

Increased:
MCV
MCH

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11
Q

What is seen clinically in thalassemia?

A

High RBC

Normal Hgb
Normal Hct

Low MCV
Low MCH

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12
Q

What is seen in barbiturate overdose?

A

Death due to respiratory arrest

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13
Q

What is seen in benzodiazepine toxicity?

A

CNS depression when combined with other CNS depressants

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14
Q

What is seen in carbon monoxide poisoning? How is it treated?

A

High binding to oxygen = slowly suffocate

Treat with fresh air, 100% oxygen

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15
Q

What is seen in fentanyl analog overdose? Treatment?

A

Death

Naloxone

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16
Q

What is prostrate specific androgen used for?

A

Monitor treatment of prostate cancer and BPH

17
Q

How is prostrate specific androgen measured?

A

ratio of free:total

18
Q

How is PT test performed?

A

Add TF and Ca to blood sample and measure time

19
Q

What is prostatic acid phosphatase used for?

A

Monitor residual/recurrent prostate cancer *low sensitivity

Lab Medicine (23 decks)

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