Lab Med 241-257 Flashcards

1
Q

When are LFT’s highest?

A

In acute hepatic necrosis

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2
Q

When are OTC pregnancy tests definitive?

A

Approximately 4 weeks after 1st day of last menses

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3
Q

When are total proteins low?

A

In starvation

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4
Q

When does bilirubinuria occur?

A

Biliary obstruction
Hepatocellular damage
Dubin-Johnson syndrome
Rotor’s syndrome

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5
Q

When is a decrease in serum iron seen?

A
Iron deficiency  
Chronic inflammatory disorders  
Hemmorrhage  
Blood donation  
Menstruation
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6
Q

When is an increase in serum iron seen?

A
After use of BC  
Iron poisoning  
Ingestion/IV  
Hepatitis  
Hemosiderosis/hemochromatosis
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7
Q

When is blood ammonia elevated?

A

Severe liver disease

impending hepatic coma

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8
Q

When is delta-bilirubin increased?

A

In prolonged conjugated hyperbilirubinemia

Causes disease to persist because highly bound to albumin

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9
Q

When is serum ferritin elevated?

A
Viral hepatitis  
Iron storage diseases  
RA  
Renal disease  
Malignancies
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10
Q

When is TIBC decreased?

A
CAMM  
Chronic inflammatory disorders 
Acute inflammation 
Malignancies 
Malnutrition
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11
Q

When is TIBC increased?

A

In iron deficiency

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12
Q

When is TSI present?

A

In Grave’s disease (mimics TSH and does not respond to feedback)

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13
Q

Where is alkaline phosphatase found?

A
Bone, 
GI, 
placenta, 
tumors, 
biliary tract
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14
Q

Where is gamma glutamyl transferase found?

A

Liver,
pancreas
kidney (high amounts)

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15
Q

Why is ethylene glycol dangerous?

A

CNS depressant with toxic metabolites (myocardial depression, renal necrosis)
Severe hypOcalcemia
Elevated osmol gap
Elevated anion gap

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16
Q

Why is isopropanol dangerous?

A

Twice the CNS depression as ethanol

Causes GI bleed and belching

17
Q

Why is quantitative iron in liver biopsies sometimes measured?

A

To diagnose hemochromatosis in cases with borderline serum iron and TIBC