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Lab Medicine > Lab Med 196-210 > Flashcards

Lab Med 196-210 Flashcards

1
Q

What is subclinical hyperthyroidism?

A

Undetectable TSH with normal total T3 and free T4 –> subtle thyrotoxicosis

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2
Q

What is subclinical hypothyroidism?

A

Elevated TSH with nomal T3 and free T4

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3
Q

What is tacrolimus?

A

Prophylactic of organ rejection in allogeneic liver or kidney transplants

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4
Q

What is thalassemia?

A

Decreased production of at least 1 hemoglobin gene product

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5
Q

What is the active metabolite in cocaine?

A

Benzoylecgonine

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6
Q

What is the CRH stimulation test used for?

A

Differentiate between Cushing’s disease and ectopic ACTH

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7
Q

What is the dexamethasone suppression test used for?

A

To determine if the hypercortisolism is pituitary dependent

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8
Q

What is the general treatment of drug overdose?

A

ABCD
Supportive care
Antidote
Peritoneal dialysis, hemodialysis, or hemoperfusion

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9
Q

What is the high dose dexamethasone suppression test?

A

Give high dose dexa Q6 for 8 doses with 24 hour urine collection and plasma cortisol day 1 and day 5

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10
Q

What is the low dose dexamethasone suppression test?

A

Give dexa every 6 hours for 48 hours

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11
Q

What is the primary screening test for thyroid function?

A

TSH

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12
Q

What is the purpose of the ACTH stimulation test?

A

Assess the ability of the adrenal cortex to respond to ACTH stimulation by production of glucocorticoids
Differentiate between 1° and 2° hypocortisolism

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13
Q

In what population is subclinical hypothyroidism seen in?

A

Most common in women over 60

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14
Q

Exaggerated CRH stimulation test response indicates _____

A

Cushing’s

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15
Q

No response to CRH stimulation test indicates _____

A

ectopic

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16
Q

Some rise in CRH stimulation test indicates ____

A

normal or tertiary

17
Q

High dexamethasone suppression test - Suppression of urinary and plasma cortisol day 5

A

Cushing’s from ACTH-pituitary adenoma

18
Q

High dexamethasone suppression test - Urinary not suppressed

A

autonomous cortisol or ectopic ACTH

19
Q

low dose dexamethasone suppression test - cortisol suppressed indicates _____

A

normal

20
Q

low dose dexamethasone suppression test - cortisol elevated indicates ____

A

possible Cushings

Lab Medicine (23 decks)

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