L19- Skin Flashcards
three main layers of the skin
epidermis
dermis
hypodermis
layers of the epidermis from outer layer inwards
Cats Gather Suspciously Boldly
- stratum corneum
- stratum granulosum
- st. spinosum
- st. basale
what structures are found in the dermis
hair follicles
arrector pili muscle
sweat glands
sebaceous gland
what type of tissue is the dermis
irregular dense connective tissue
thickness of hypodermis varies in
ifferent regions of the body and can vary considerably between different people
Thickness plays an important role in distinguishing between males and females
hypodermis in men
hypodermis is thickest in the abdomen and shoulders
hypodermis in women
thickest in the hips, thighs, and buttocks
hypodermis is the
lowest layer of the skin
hypodermis also known as
subcutaneous layer
structure of hypodermis
- Mainly contains adipose tissue
• Loose connective tissue – fibroblasts/ macrophages/fibres
function of hypodermis
- energy store- generates heat
- insulator for udnelryign muscl eheat gen
- shock absorber
- conencts skin to underlying muscle and bone
- makes hormones
dermis located
between epidermis and hypodermis
structure of dermis
Three layers
• Papillary - upper
- Reticular - lower
- Dermal papillae – interdigitating
dermis shows…
vairbale thickness
0.6 mm on eyelid; 3 mm on hands/feet
function of dermis
• Contains hairs and sweat glands - thermoregulation • Contains sensory structures – special senses - touch • Gives structure to skin and so body shape
epidermis location
Outermost layer made of epithelial cells (keratinocytes)
structure of epidermis
- Four layers of cells (thin skin)
- Five layers (thick skin)
- Held together (laterally) by adherens junctions • Some terminal nerve endings
- NO blood vessels
function of epdiermis
- Prevents water loss
- Prevents entry to bacteria and parasites
- Special cells that present pathogens to immune cells • Synthesis of keratin
- Prevents underlying tissue loss due to abrasion
stratum corneum
Outermost layer made of squames (dead keratinocytes)
stratum corenum on paalms and soles of feet
thickest- prone to injury- continously shed
strautum lucidum is
transparent
where is stratum lucidum found
palms and soles
stratum granulosum
- stratified squamous epithelium
- lamellar granules
- tonofibrils
lamellar granules
filament-associated proteins that assemble keratin fibrils and secrete it
tonofibrils
bundles of keratin filaments and keratohyalin granules- made by lamellar bodies
stratum spinosum
3 layers of cubodial epithelium (held together by desmosomes)
- producers of lamellar bodies
- first time golgi apparatus appears
lamellar bodies
keratin factories
stratum basale
Tall columnar epithelial cells
Constantly renew keratinocytes by cell division
As daughter cells differentiate they move away from the epidermis-dermis junction
These make keratin filaments (tonofilaments) They lose their ability to divide
Also home to the melanocytes – produce melanin
ketatinocytes synthesise
keratins that cotnribute to the strength of the epidermis
(keratin- main constituents of hair and nail, and animal horns)
normla transit tiem of keratinocytes from basale to stratum conreum
28-40 days