Bone from website Flashcards

1
Q

function of bone

A
  1. protect vital organs 2. store minerals such as calcium 3. store lipids (white bone marrow) 4. Make blood cells (haemopoesis)
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2
Q

when the body needs calcium

A

the bone releases calcium

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3
Q

calcium necessary for

A

muscle cotnraction, blood clotting, nerve conduction.., strength of bones andf teeth

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4
Q

osteoclasts break down bone to

A

free calcium

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5
Q

osteoblasts deposit

A

calcium in bone, remaking it

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6
Q

bone cells are called

A

osteocytes

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7
Q

osteocytes are found within

A

lucunae in each lacuna you will find one osteocyte

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8
Q

canaliculi

A

connect lacuna allowing osteocytes to communicate with eachother via their processes (filapodia)

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9
Q

two types of bone

A

compact cancellaneous (spongy)

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10
Q

compact bone found

A

under the periosteum and in the diaphyses of long bones, where it provides support and protection.

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11
Q

compact bone arranged into many

A

osteons- very regular pattern

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12
Q

overview of osteon structure

A

The osteocytes sit in their lacunae in concentric rings around a central Haversian canal (which runs longitudinally).

The osteocytes are arranged in concentric rings of bone matrix called lamellae (little plates), and their processes run in interconnecting canaliculi.

The central Haversian canal, and horizontal canals (perforating/Volkmann’s) canals contain blood vessels and nerves from the periosteum.

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13
Q

down the centre of an osteon is the

A

haversion canal

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14
Q

what is found within the haversion canal

A

blood vessels, nerves and lymphatic vessels

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15
Q

horizontal canals that flows between osteons

A

Volkmann canals - larger blood vessels and nerves - means there is a blood supply for all the bone tissue

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16
Q

two kinds of bone including compact, whoch is the other

A

Cancellous bone

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17
Q

cancellous bone

A

also known as spongy or trabecular bone, is one of the two types of bone tissue found in the human body. Cancellous bone is found at the ends of long bones, as well as in the pelvic bones, ribs, skull, and the vertebrae in the spinal column

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18
Q

difference between Cancellous (spongy bone) and compact bone

A

much less dense and less regular

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19
Q

what is the outer most layer of bone (continous with ligaments and tendons)

A

periosteum

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20
Q

down the centre of the long bone is the

A

medullary cavity

21
Q

medullary cavity contains

A

yellow bone marrow

contains largest blood vessels/ nerves

22
Q

blood vessels and nerves in the medullary cavity

A

enter the bone tissue and allow for noruishment of individual osteocytes

23
Q

endosteum

A

The endosteum (plural endostea) is a thin vascular membrane of connective tissue that lines the inner surface of the bony tissue that forms the medullary cavity of long bones.

24
Q

outline the gross structure of a long bone

A

epiphysis

metaphysis

diaphysis

25
Q

where is red bone marrow found

A

at the proximal and distal end sof the bone within spongy cancellous bone

26
Q

outer layer of bone composed of

A

compact bone

27
Q

compact bone

A

dense material with low porosity

28
Q

spongy cancellous (trabecular) tissue

A
29
Q

red bone marrow

A

makes blood cells- haemopoesis

30
Q

yellow bone marrow

A
31
Q

shape of osteocyte

A

star shaoed- long projections (filipodia/ processes) that prokect into canaliculi

32
Q

structure of spongy bone looks like

A

honeycombe

33
Q

each rod of bone in spongy bone that looks like honeycomb is called

A

a trabecula or spicule

34
Q

trabeculae (in spongy bone) dont contain

A

osteons

haversian

35
Q

matrix of spongy bone

A

o contain lamellae, or layers of bone matrix, but the lamellae are parallel to each other. The matrix contains lacunae and canaliculi, as well as osteocytes, osteoblasts, and osteoclasts.

36
Q

when the amount of bone manufacture equals the amoutn of disintegrations

A

the mass of a bone stays the same

37
Q
A
38
Q

how do osteoblasts form new bone

A

osteoblasts move over the matrix of a bone and deposit a protein mixture called osteoid. The osteoid contains a protein called collagen as its major component. Then the osteoblasts deposit minerals—including calcium—into the osteoid to make bone. The new material fills in the cavity formed by osteoclasts.

39
Q

osteocytes

A

Some osteoblasts become trapped in the bone matrix and are transformed into osteocytes inside lacunae. Osteocytes are thought to be sensory cells that are involved in signaling processes inside the bone. They connect to other osteocytes through their projections, which extend through the canaliculi. They are the most abundant cells in bone and also appear to have the longest lifespan.

40
Q

osteoclasts

A

Unlike osteoblasts, osteoclasts contain more than one nucleus. They are large cells produced by the fusion of several smaller ones. Osteoclasts travel over the surface of the bone matrix and secrete acids and enzymes to disintegrate it, forming a little pit on the surface of the bone.

  • absrob mineral- which is later relased intot he tissue fluid located between cells
  • fromt here the ions enter the blood
41
Q

which hormone stimulate sthe action of osteoclasts

A

parathyroid hormone

42
Q

parathyroid hormone

A

stimulates the action of osteoclasts when the amount of calcium in the blood falls. The hormone causes the transfer of calcium from bone to blood.

43
Q

which thryoid hormone is produced which slows the activity of osteoclasts- decreasing the bone breakdown

A

calcitonin

44
Q

what can help increase bone production

A

when someone performs regular weight-bearing exercise

45
Q

when someone is bedridden the net effect is

A

bone loss

46
Q

which hormones in men and women help maintain bone strength

A

testosterone- men

oestrogen- women

47
Q

osteoporosis summary

A

Osteoporosis is a disorder in which the bones become unusually porous and brittle and bone density decreases. The condition generally appears in older people, although it occurs in young ones as well. In osteoporosis the amount of bone resorption is much higher than the amount of bone production.

Osteoporosis can occur in both males and females, but it’s most common in post-menopausal women. After menopause the amount of estrogen in a women’s body decreases significantly, increasing the risk of weakened bones.

48
Q

general cause of osteoporosis

A

amount of bone resorption is much higher than the amount of bone production