L12- Adipose tissue Flashcards

1
Q

adipose tissue is a type of

A

connective tissue

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2
Q

function of adipose tissue (3)

A
  • protecting: shock absorber
  • insulating
  • storage fuel
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3
Q

how many types of adipocytes

A

2

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4
Q

name two adipocytes

A

white and brown adipose tissue

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5
Q

function of white adipocytes

A
  • passing and shock absorber
  • insulation
  • energy reserve
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6
Q

function of brown adipocytes

A
  • provide insulation and energy reserve to neonates
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7
Q

white adipocytes are

A

unilocular

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8
Q

how many lipid droplets in white adipocytes

A

one single enormous lipid droplet

- nucleus, cytoplasm and organelles all squeeze to one side

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9
Q

fat adipocytes are

A

multilocular

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10
Q

where is nucleus found in brown fat

A

in the centre

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11
Q

lipid droplets in brown fat

A

multiple small lipid droplets with nucleus and cytoplasm squeezed int he centre of the cell

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12
Q

difference between brown fat and white fat

A
  • white has one single lipid droplet, brown has many lipid droplets
  • white is unilocular, brown is multilocular

Brown fat has LOTS OF MITOCHONDRIA

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13
Q

how much brown fat found in adults

A

very little

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14
Q

brown adipose tissue contains

A

naturally occurring uncoupling proteins

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15
Q

name a naturally occurring uncoupling protein

A

thermogenin

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16
Q

thermogenin also known as

A

UCP1

17
Q

newborn infants and hibernating animals have lots of brown adipose to

A

maintain body heat around vital organs

18
Q

in response to col what is released

A

noradrenaline

19
Q

noradrenaline activates

A
  1. lipase which releases fatty acids from from TAG in liver
  2. fatty acid oxidation = production of NADH/FADH2 –> ETC
  3. Fatty acids activate UCP1
  4. UCP1 transports H+ back into mitochondria

SO electron transport is uncoupled from ATP synthesis
- energy of proton motive force released as extra heat