Ischemic Heart Disease Flashcards
Chest pain that is predictable, occurs with activity/stress, relieved by rest or nitro
Stable ischemic heart disease
-usual underlying cause is atherosclerosis (CAD)
Vasospasm of the coronary arteries, occurs at rest, caused by cocaine
Prinzmetal’s angina
Acute chest pain that is severe and no relieved by rest/nitro
Acute coronary syndromes
-UA, STEMI, NSTEMI
Meds for Stable Ischemic Heart Disease
Antiplatelet + Antianginal
ASA/Clopidogrel + BB/CCB + nitrate
Drug Tx for ACS (UA, NSTEMI, STEMI) in hosp
MONA
Morphine, Oxygen, Nitrates, ASA
When the heart is not able to supply sufficient oxygen-rich blood to the body because of impaired ability of the ventricle to either fill or eject blood
Heart failure
HF is mostly due to
An MI (ischemic) Or HTN (non-ischemic)
Ejection fraction (left ventricular) measures
How much blood is being pumped out with each contraction
An EF of less than ____% indicated systolic dysfunction or HF with reduced EF
40%
Top number on a BP reading
Systolic - contraction
Bottom number on BP reading
Diastolic - relaxation
Weight to notify MD in HF
Increase of 2-4 lbs in 1 day OR
Increase of 3-5 lbs in 1 week
Drugs that cause or worsen HF
Drug Information NATION DPP4s (-gliptans) Immunosuppressants (TNF inhibitors) Non-DHP CCBs (verapamil & diltiazem) Antiarrythmics (Class I agents) Thiazolidinediones Irtaconazole Oncology agents(doxorubicin) NSAIDs
Drug tx of HF
Combo of ACE/ARB + BB + loop
-next would add aldosterone receptor agonist
What does digoxin do for the heart
Increases cardiac output (vol of blood pumped pumped by the heart)