Integumentary/Immune System

Question 1

Dermis

Answer 1

Contains blood supply to the skin and most of the specialized cells

Question 2

Epidermis

Answer 2

It contains mainly keratinocytes (corneocytes) or waterproof cells and sloughs off

Question 3

5 Layers of the Epidermis

Answer 3

corneum, lucidum, granulosum, spinosum, basale

Question 4

Innate Immunity

Answer 4

The body’s initial generalized defense against pathogens, inflammation, physiologic response

Question 5

Granulocytes

Answer 5

Attracted to the site of injury, phagocytize antigens and antigenetic material

Question 6

3 Types of Granulocytes

Answer 6

Neutrophils, Eosinophils, Basophils

Question 7

Neutrophils

Answer 7

Most common, first responders to sites of inflammation, attracted to cytokines, adapted to attack bacteria, main component of pus

Question 8

Eosinophils

Answer 8

Responsible for immune responses, allergic and asthmatic responses

Question 9

Basophils

Answer 9

Mast cells, allergic response, release of histamine, blood vessel dilation

Question 10

Monocytes

Answer 10

Large, long-lived immune cells that can differentiate into macrophages and dendritic cells

Question 11

Macrophages

Answer 11

Phagocytize dead cells and pathogens

Question 12

Dendritic Cells

Answer 12

Process antigens and present them to other immune cells, link between innate and adaptive immune response

Question 13

Adaptive Immunity Cells

Answer 13

B Cells, T Cells (CD4+,CD8+), Antibodies

Question 14

Innate Immunity Cells

Answer 14

Macrophages, Natural Killer Cells, Basophils, Eosinophils, Neutrophils

Question 15

T lymphocytes

Answer 15

cell-mediated immunity, development in bone marrow, travel to the thymus for maturation, released into the lymph to perform immune functions

Question 16

Major Histocompatibility Protein Complex

Answer 16

Indicate that the corresponding T cell should perform its function, presents the antigen of the pathogen

Question 17

CD8+ T cells

Answer 17

Cytotoxic T cells, recognize and respond to antigens presented by MHC I complexes

Question 18

CD4+ T cells

Answer 18

T helper cells, recognize and respond to antigens presented by MHC II complexes

Question 19

Natural Killer T cells

Answer 19

Respond to antigens presented by other types of cells

Question 20

B lymphocytes

Answer 20

Begin development in the bone marrow, they do not travel to other part of the body, creat and express antibodies that have high affinity for antigens

Question 21

Structure of immunoglobulins

Answer 21

Resembles a “Y” with antigens binding sites at either end of the “Y”, each side contains two chains, light and heavy

Question 22

N site

Answer 22

Antigen binding site

Question 23

C site

Answer 23

Cell-receptor binding region

Question 24

Active Immunity

Answer 24

result of the immune response, due to exposure or vaccination

Question 25

Passive Immunity

Answer 25

Acquired by the transfer of antibodies from one individual to another, pregnancy (maternal antibodies)

Question 26

Lymph

Answer 26

Flows through the lymphatic vessels from lymph node to lymph node

Question 27

Lymph node

Answer 27

reservoirs of white blood cells (like spleen), filter for lymph, removing antigen-presenting cells and foreign matter

Question 28

What is the role of histamine in the immune response?

Answer 28

To dilate the blood vessels

Question 29

What type of cell responds to activated MHC II complexes?

Answer 29

Helper T cells (CD4+)

Question 30

Which cells produce a memory-driven response to pathogens?

Answer 30

B lymphocytes

Question 31

Where is the antigen-binding region found on the immunoglobulin structure?

Answer 31

N-terminus