Innate and Adaptive Immunity (5/16) Flashcards
Innate immunity
broad, non-specific protection against microbes to prevent infections
Adaptive immunity
very specific to it’s targets
antibodies
Functions of innate immune system
preventing them from getting in from skin, lysozyme in mouth (breaks down bacterial cell walls), mucus, tympanic membrane in ear
Cellular response
neutrophil first at scene of infection
macrophages, dendritic cells, basophils
Cytokines
respond to inflammatory responses
Lymphocytes in adaptive immune system
T cells and B cells
antigen specific
Positive-negative selection
positive for T cells that do want to react
negative for T cells that are too reactive
T cell classes
MHC1 receptors
damaged cell, CD8 T cells (killer T cells)
MHC2 receptors only on certain immune cells like macrophases and dendritic cells
CD4 T-cells- helper T cells to secrete cytokines to recruit more immune cells like neutrophils
CD8 and CD4 T cells after doing their job…
can become memory T cells
Humoral response
B cells
B cells
produced in bone marrow and mature there. produce antibodies
when presented with a antigen, can either become a short lived cell or a memory cell