Endocrine Glands, Hormones, and Functions (5/14) Flashcards
Hypothalamus role
Bridge between nervous and endocrine systems
Hypothalamus job
controls things such as body temperature, metabolism, fatigue, and sleep. Oversees activity of pituitary gland
Pituitary gland anatomy
Contains an anterior and posterior lobe and receive information from hypothalamus
The anterior lobe of the pituitary gland
received signals from hypothalamus via hormones
The posterior globe of the pituitary gland
receives signals from the hypothalamus via neuronal signals
The connection between the anterior lobe of the pituitary gland, and the hypothalamus
the hypophyseal portal system
Tropic hormones
Hormones that act on other endocrine glands
Tropic hormones naming
something-releasing and then something-stimulating
then something
Example of thyrotropin-releasing hormone
TRH gets released from the hypothalamus and signals the anterior pituitary gland to release thyroid-stimulating hormone for the thyroid gland to release T3 and T4
GnRH
released from hypothalamus for LH and FSH to be released from anterior pituitary lobe
FSH: maturation of ovary and release of testosterone
LH: promotes spermatogenesis or estrogen
CRH
ACTH gets released from anterior pituitary and goes to adrenal glands to release corticosteroids to control stress and circadian rhythms
GHRH
GH in times of stress and is involved in blood glucose (gets released from anterior pituitary)
Prolactin
released from AP and acts on mammary glands
Endorphins
released from AP and reduced perception of pain
Similarities between AP and PP
Secrete peptide hormones and receive hypothalamic input
Posterior pituitary
bundle of neuromal axons
hormones are made in hypothalamus and goes to PP and when stimulation comes, it gets released from PP
Oxytocin and ADH (vasopressin)
ADH- released when dehydrated
Oxytocin- labor contraction, lactation, and social bonding
Thyroid
anterior on trachea, right below adam’s apple
secretes T3 and T4
Parathyroid glands
4 small glands located on the posterior side of the thyroid
release PTH- increase calcium circular levels
Adrenal glands
sits on top of kidney
medulla- surrounded by cortex
Cortex releases corticosteroids
What are the classes of corticosteroids that the cortex of the adrenal glands release?
Glucocorticoids Mineralocorticoids Sex hormones (sugar, salt, and sex) Released by ATCH from anterior pituitary gland
Cortisol (Glucocorticoids)
Released from the adrenal cortex in response to stress and low blood pressure. Increases blood glucose levels and suppressing inflammatory immune responses
Adrenal medulla
produces epinephrine and norepinephrine
belong to a larger group of hormones called catecholamines
Pancreas
Alpha cells
Beta cells
Detla cells
Alpha cells
Glucagon
Beta cells
Insulin
Delta cells
Somatostatin
Pineal gland
secretes melatonin to regulate sleep cycles and wakefulness
Atrial natriuretic peptide
released in response to high blood volume to regulate fluid balance
Thymus
Thymosin- helps T-cells development and mature
Digestive system
Gastrin, CCK, and secretin
Blood glucose levels
insulin and glucagon
Cortisol- increases blood glucose in fasted state
Epinephrine- raises blood glucose (flight or fight)
GH- increase blood glucose when stressed
Calcium regulation
PTH- secreted by parathyroid gland to raise
Calcitonin- released by thyroid gland to lower
Vitamin D- promotes absorption
Fluid balance
too little: high blood osmolality
Aldosterone- works with RASS and renin releases angiotensin I and gets converted to II and stimulates aldosterone release
ADH aka vasopressin
RAAS dysregulation
can cause a dangerous rise in blood pressure
ANP
produced by the heart and released to high blood pressure and decrease sodium absorption (lowers blood pressure for fluid loss)
Acute stress
fight or flight
epinephrine and norepinephrine called catecholamines
increase blood glucose levels
Chronic stress
repeated exposure to stressful situations
cortisol
increases blood glucose levels
suppresses inflammation
Metabolic rate
T3 and T4
Hypothyroidism
insufficient T3 and T3
fatigue, cold intolerance, weight gain, depressed heart and respiratory rates
Sexual development: female
LH: ovaries produce estrogen
FSH: