Circulatory System Flashcards
Blood structure
plasma- fluid component (55%) and carries ions, nutrients, and gases
buffy coat- 1% and contains white blood cells and platelets
red blood cells- 45%, hematocrit. carries gases like CO2 and O2
Platelets
Cell fragments and are essential for coagulation (blood clotting) and are derived from megakaryocytes
Coagulation cascade
Clotting factors have Prothrombin be converted to Thromin which is then converted to Fibrinogen and the Fibrin
Erythrocytes and their glycoproteins
This is what ABO blood typing is based off of
Rh factor
+= have the factor
Erythropoietin
it is released from the kidney and its role is stimulation of red blood cell development
The two parts of the cardiovascular system
systemic circulation
pulmonary circulation
systemic
takes oxygen rich blood to tissues and the returns the now oxygen depleted blood to the heart
Pulmonary circulation
circulatory system through the lungs
Arteries function
carry blood away from the heart
arteries of systemic circulation carry oxygenated blood to tissues, but the pulmonary artery carries de-oxygenated blood from the heart to the lungs. also, umbilical artery carries de-oxygenated blood from fetus to placenta to become oxygenated to return back to fetus
Artery anatomy
Have a thick muscular wall and are adaptable. branch off into arterioles and lead to capillaries
Veins
carry blood to heart. start off as venules and become larger. BP is low in veins
How is the gravity issue solved when returning blood to heart through veins?
A valve allows to go to heart, but prevents back flow. Also, skeletal muscle helps
The layers of blood vessels
Tunica externa Tunica media Tunica intima (thin layer of endothelial cells)
Atherosclerosis
Fatty plaque build up in arteries. can lead to heart attack if build up is in heart