Inhibidores de pared bacteriana (rbnn) Flashcards

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1
Q

RAF de importancia para Penicilina

A

Sx Jarisch Herpxheimer
- como parte de respuesta al Tx de treponema
- rash, fiebre, mialgias,

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1
Q

Indicacion de Dicloxicacilina

A

Al ser hidrofóbica ataca principalmente a S. Aureus, son estructuralmente resistentes a B- Lactamasas

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2
Q

Aminopenicilina

A

Amoxicilina

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3
Q

Indicaciones de Amoxicilina

A
  • OMA y endocarditis por Strep y Staph
  • H. Pylori
  • Enterococcus y proteus
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4
Q

Contraindicaciones de Amoxicilina

A

Mononucleosis -> genre fenilcetonuria

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5
Q

Hallazgos del Tx con Amoxicilina

A
  • Disminuye la [ otros fármacos]
  • Aumenta el efecto anticoagulante
  • GENERA FALSA GLUCOSA EN ORINA
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6
Q

Respectivamente
requieren de co -administración con Cilastatina

A

Cilastatina
✗ Meropenem
✓ Imipenem

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7
Q

Respectivamente
son propensos a genrar convulsiones

A

✗ Meropenem
✓ Imipenem, también disminuye el hematocrito y hemoglobina

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8
Q

Usa ______ para su metabolismo

A

Dipeptidasa en el tubo proximal

✗ Meropenem
✓ Imipenem

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9
Q

Indicación y RAF de clavulonato

A

OMA, IVUs e IRAs

RAF : candidiasis oral

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10
Q

Contraindication de clavulonato

A

Asma
Fiebre del heno
Mononucleosis

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11
Q

mecanismoS de acción de vancomicina

A
  • U a terminar D-Ala-D-Ala
  • Inhibe a RNA sintasa
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12
Q

indicacion de vancomicinma

A

Endocarditis, Sepsis (IV)
Tejidos blancos (IM)
Inf. GI (Oral)
C. diffile

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13
Q

Relevancia de la Farmaco K de vancomicina

A

No se absorbe entonces sale por heces y puede atacar a C, difficile

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14
Q

RAF comunes de Vancomicina

A
  • Sx del hombre rojo por aumento de histamina
  • Nefrotoxicidad
  • otoxicidad (potenciada por gentamicina)
  • Neutropenia
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