Inflammation (Acute vs. Chronic)

Question 1

Path

Answer 1

AI: microbial pathogens, trauma, burns
CI: persistant acute inflamm, foreign bodies, autoimmune dz, certain inf (TB, leprosy)

Question 2

primary cells involved

Answer 2

AI: neutrophils
CI: monocytes/macrophages (key), B/T lymphocytes, plasma cells, fibroblasts

Question 3

primary mediators

Answer 3

AI: histamine (key), prostaglandins, leukotrienes
CI: cytokines (IL-1), growth factors

Question 4

necrosis

Answer 4

AI: present
CI: less prominent

Question 5

scar tissue

Answer 5

AI: absent
CI: present

Question 6

onset

Answer 6

AI: immediate
CI: delayed

Question 7

duration

Answer 7

AI: few days
CI: weeks to years

Question 8

outcome

Answer 8

AI: complete resolution, abscess formation, progress to chronic inflamm
CI: scar tissue, disability, amyloidosis

Question 9

main Ig

Answer 9

AI: IgM
CI: IgG

Question 10

SPE effect

Answer 10

AI: mild hypoalbuminemia, normal gamma-globulin peak
CI: polyclonal gammopathy, greater degree of hypoalbuminemia

Question 11

peripheral blood leukocyte response

Answer 11

AI: neutrophilic leukocytosis
CI: monocytosis

Question 12

what is rubor?

Answer 12

redness

Question 13

what is calor?

Answer 13

heat

Question 14

what is dolor?

Answer 14

pain

Question 15

what is tumor?

Answer 15

swelling

Question 16

what is functio laesa?

Answer 16

loss of function