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USMLE Step 1 Random Facts > Drug rxns > Flashcards

Drug rxns Flashcards

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USMLE® Step 1 flashcards
1
Q

coronary vasospasm

A

cocaine
sumatriptan
ergot alkaloids

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2
Q

cutaneous flushing

A

vancomycin
adenosine
niacin
CCB

“VANC”

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3
Q

dilated cardiomyopathy

A

doxorubicin (adriamycin)

daunorubicin

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4
Q

torsades de pointes

A

class III (sotalol) and class IA (quinidine) antiarrhythmics

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5
Q

agranulocytosis

A 
clozapine
carbamazepine
cochicine
PTU
methimazole
dapsone

“Agranulocytosis Could Certainly Cause Pretty Major Damage”

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6
Q

Aplastic anemia

A 
chloramphenicol
benzene
NSAIDs
PTU
methimazole
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7
Q

direct Coombs-positive hemolytic anemia

A

methyldopa

penicillin

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8
Q

gray baby synd

A

chloramphenicol

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9
Q

hemolysis in G6PD-deficient pts

A 
isoniazid
sulfonamides
primaquine
aspirin
ibuprofen
nitrofuratoin

“hemolysis IS PAIN”

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10
Q

megaloblastic anemia

A

phenytoin
methotrexate
sulfa drugs

“having a BLAST w/ PMS”

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11
Q

thrombotic complications

A

OCPs (eg. estrogen)

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12
Q

cough

A

ACE inhibitors

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13
Q

pulmonary fibrosis

A

bleomycin
amiodarone
busulfan

“it’s hard to BLAB when you have pulm fibrosis”

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14
Q

acute cholestatic hepatitis, jaundice

A

erythromycin

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15
Q

focal to massive hepatic necrosis

A

halothane
amanita phalloides
valproic acid
acetominophen

“liver HAVAc”

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16
Q

hepatitis

A

INH

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17
Q

pseudomembranous colitis

A

clindamycin

ampicillin

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18
Q

adrenocortical insuff

A

glucocorticoid withdrawal (HPA suppression)

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19
Q

gynecomastia

A 
spironolactone
digitalis
cimetidine
chronic alcohol use
estrogens
ketoconazole

“Some Drugs Create Awkward Knockers”

20
Q

hot flashes

A

tamoxifen

clomiphene

21
Q

hyperglycemia

A 
niacin
tacrolimus
protease inhibitors
HCTZ
corticosteroids
22
Q

hypothyroidism

A

lithium
amiodarone
sulfonamides

23
Q

fat redistribution

A

glucocorticoids

protease inhibitors

24
Q

gingival hyperplasia

A

phenytoin

verapamil

25
Q

gout

A

furosemide
thiazides
niacin
cyclosporine

26
Q

myopathies

A 
Fibrates
Niacin
Colchicine
Hydroxychloroquine
IFN-alpha
Penicillamine
Statins
Glucocorticoids

“Fish N CHIPS Give you myopathies”

statins + fibrates greatly increases risk

27
Q

osteoporosis

A

corticosteroids

heparin

28
Q

photosensitivity

A

Sulfonamides
Amiodarone
Tetracycline

“SAT for a photo”

29
Q

Rash (Stevens-Johnson synd)

A 
Pencillin
Ethosuxamide
Carbamazepine
Sulfa drugs
Lamotrigine
Allopurinol
Phenytoin
Phenobarbital

“bad rash after a PEC SLAPP”

3 main categories that cause it: penicillin, sulfa drugs, seizure drugs

30
Q

SLE-like synd

A

Hydralazine
INH
Procainamide
Phenytoin

“it’s not HIPP to have lupus”

31
Q

Teeth (kids)

A

tetracyclines

32
Q

tendonitis, tendon rupture, cartilage damage

A

fluoroquinolones

33
Q

diabetes insipidus

A

Lithium

demeclocycline

34
Q

Fanconi’s synd (disease of the proximal renal tubules of the kidney in which glucose, amino acids, uric acid, phosphate and bicarbonate are passed into the urine instead of being reabsorbed)

A

expired tetracycline

35
Q

hemorrhagic cystitis

A

cyclophosphamide
ifosfamide

**prevent by co-admin w/ mesna

36
Q

interstitial nephritis

A

methicillin
NSAIDs
furosemide

37
Q

SIADH

A

cabamazepine

cyclophosphamide

38
Q

cinchonism (temporary deafness, ringing in the ears, headache, dizziness, and rash)

A

Quinidine

quinine

39
Q

parkinson-like synd

A

antipsychotics
reserpine
metoclopramide

40
Q

Seizures

A 
Isoniazid
Bupropion
Imipenem/cilastatin
Tramadol
Enflurane
Metoclopramide

“with seizures, I BITE My tongue”

41
Q

Tardive dyskinesia

A

antipsychotics

42
Q

antimuscarinic

A

atropine
TCAs
H1 blockers
neuroleptics

43
Q

disulfiram-like rxn

A 
metronidazole
certain cephalosporins (cefoperazone and cefotetan)
procarbazine
1st gen sulfonylureas
griseofulvin
44
Q

Nephrotoxicity/otoxicity

A

aminoglycosides
vancomycin
loop diuretics
cisplatin

45
Q

blurry yellow vision

A

digoxin

USMLE Step 1 Random Facts (35 decks)

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