Drug rxns Flashcards
coronary vasospasm
cocaine
sumatriptan
ergot alkaloids
cutaneous flushing
vancomycin
adenosine
niacin
CCB
“VANC”
dilated cardiomyopathy
doxorubicin (adriamycin)
daunorubicin
torsades de pointes
class III (sotalol) and class IA (quinidine) antiarrhythmics
agranulocytosis
clozapine carbamazepine cochicine PTU methimazole dapsone
“Agranulocytosis Could Certainly Cause Pretty Major Damage”
Aplastic anemia
chloramphenicol benzene NSAIDs PTU methimazole
direct Coombs-positive hemolytic anemia
methyldopa
penicillin
gray baby synd
chloramphenicol
hemolysis in G6PD-deficient pts
isoniazid sulfonamides primaquine aspirin ibuprofen nitrofuratoin
“hemolysis IS PAIN”
megaloblastic anemia
phenytoin
methotrexate
sulfa drugs
“having a BLAST w/ PMS”
thrombotic complications
OCPs (eg. estrogen)
cough
ACE inhibitors
pulmonary fibrosis
bleomycin
amiodarone
busulfan
“it’s hard to BLAB when you have pulm fibrosis”
acute cholestatic hepatitis, jaundice
erythromycin
focal to massive hepatic necrosis
halothane
amanita phalloides
valproic acid
acetominophen
“liver HAVAc”
hepatitis
INH
pseudomembranous colitis
clindamycin
ampicillin
adrenocortical insuff
glucocorticoid withdrawal (HPA suppression)
gynecomastia
spironolactone digitalis cimetidine chronic alcohol use estrogens ketoconazole
“Some Drugs Create Awkward Knockers”
hot flashes
tamoxifen
clomiphene
hyperglycemia
niacin tacrolimus protease inhibitors HCTZ corticosteroids
hypothyroidism
lithium
amiodarone
sulfonamides
fat redistribution
glucocorticoids
protease inhibitors
gingival hyperplasia
phenytoin
verapamil
gout
furosemide
thiazides
niacin
cyclosporine
myopathies
Fibrates Niacin Colchicine Hydroxychloroquine IFN-alpha Penicillamine Statins Glucocorticoids
“Fish N CHIPS Give you myopathies”
statins + fibrates greatly increases risk
osteoporosis
corticosteroids
heparin
photosensitivity
Sulfonamides
Amiodarone
Tetracycline
“SAT for a photo”
Rash (Stevens-Johnson synd)
Pencillin Ethosuxamide Carbamazepine Sulfa drugs Lamotrigine Allopurinol Phenytoin Phenobarbital
“bad rash after a PEC SLAPP”
3 main categories that cause it: penicillin, sulfa drugs, seizure drugs
SLE-like synd
Hydralazine
INH
Procainamide
Phenytoin
“it’s not HIPP to have lupus”
Teeth (kids)
tetracyclines
tendonitis, tendon rupture, cartilage damage
fluoroquinolones
diabetes insipidus
Lithium
demeclocycline
Fanconi’s synd (disease of the proximal renal tubules of the kidney in which glucose, amino acids, uric acid, phosphate and bicarbonate are passed into the urine instead of being reabsorbed)
expired tetracycline
hemorrhagic cystitis
cyclophosphamide
ifosfamide
**prevent by co-admin w/ mesna
interstitial nephritis
methicillin
NSAIDs
furosemide
SIADH
cabamazepine
cyclophosphamide
cinchonism (temporary deafness, ringing in the ears, headache, dizziness, and rash)
Quinidine
quinine
parkinson-like synd
antipsychotics
reserpine
metoclopramide
Seizures
Isoniazid Bupropion Imipenem/cilastatin Tramadol Enflurane Metoclopramide
“with seizures, I BITE My tongue”
Tardive dyskinesia
antipsychotics
antimuscarinic
atropine
TCAs
H1 blockers
neuroleptics
disulfiram-like rxn
metronidazole certain cephalosporins (cefoperazone and cefotetan) procarbazine 1st gen sulfonylureas griseofulvin
Nephrotoxicity/otoxicity
aminoglycosides
vancomycin
loop diuretics
cisplatin
blurry yellow vision
digoxin
