Cholinergic Pharmacology Flashcards
Tissue/ACh effects (except effects of ganglionic blockade cards)
vasculature (endothelial cells)
release of NO and vasodilation
eye iris (pupillae sphincter muscle)
contraction and miosis
ciliary muscle
contraction and accommodation of lens to near vision
salivary and lacrimal glands
thin and watery secretions
bronchi
constriction; increase secretions
heart
bradycardia, decrease conduction velocity, AV block at HIGH doses, slight decrease in contractility
GI tract
increase tone and secretions; relax sphincters
urinary bladder
contraction of detrusor muscle
relaxation of sphincter
sweat glands
diaphoresis (profuse sweating)
reproductive tract, male
erection
uterus
variable
blockade of sympathetics in arterioles
vasodilation
increase peripheral blood flow
hypotension
blockade of sympathetics in veins
vasodilation
pooling of blood
DECREASE venous return
DECREASE cardiac output
