hypersensitivity exam 4 Flashcards

1
Q

what is hypersensitivity

A

Hypersensitivity is a NORMAL immune response that is:
-inappropriately triggered
OR
-excessive
OR
-produces undesirable effects on the body

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2
Q

how are types I, II, III mediated

A

mediated by ANTIBODIES produced by B cells

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3
Q

how is type IV mediated

A

mediated by T cells

-delayed response

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4
Q

What is type I

A

IgE mediated reaction

- in response to someone reacting from allergy

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5
Q

what is type II

A

cytotoxic reaction

-giving someone the wrong type of blood

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6
Q

what antibodies are involved in type II

A

IgG and IgM

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7
Q

What is type III

A

immune complex reaction

-antigen antibody complex; causing inflammation

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8
Q

what is difference between type II and type III

A

type II - direct cell death

type III - don’t actually destroy; inflammation destroys

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9
Q

what is type IV

A

delayed hypersensitivity

-poison ivy, positive TB skin test, jewelry

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10
Q

what cells does type IV involve

A

T-cells not antibodies

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11
Q

how does epinephrine work in the body

A

inhibits release of mediators from mast cells

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