Diabetes Pathophysiology Exam 2 Flashcards

1
Q

What is diabetes

A

metabolic disorder characterized by HYPERGLYCEMIA that results form defects in insulin secretion, insulin action, or both

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2
Q

where in pancreas does endocrine function occur?

A

Islet of Langerhans

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3
Q

what do alpha cells do

A

secrete glucagon in response to low blood sugar

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4
Q

glucagon

A

stimulates the liver to release stored glucose into the blood

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5
Q

beta cells

A

produce insulin which lowers glucose levels by stimulating the movement of glucose into body tissues

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6
Q

Insulin

A

secreted by the pancreas (beta cells), stimulates uptake, utilization, and storage of glucose, stimulates the liver to store glucose (as glycogen)

b/c of stimulating effects– insulin decreases plasma concentrations of glucose

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7
Q

insulin and fat

A

insulin promotes synthesis of fatty acids in the liver

insulin inhibits the breakdown of fat in the adipose tissue – can cause a buildup of triglycerides in fat cells

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8
Q

when our body begins to break down fat.. what is the by product?

A

Free Fatty Acid (FFA)

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9
Q

when you breakdown protein what is by product?

A

amino acids

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10
Q

S/S of hypoglycemia

A

pallor, sweating, tachycardia, palpitations, hunger, restlessness, anxiety, tremors, convulsion, coma

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11
Q

Somogyi effect

A

overdose of insulin which causes hypoglycemia and counter regulatory mechanisms cause hyperglycemia and ketosis

liver sense low blood sugar, releases stored glucose = hyperglycemia and ketosis

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12
Q

dawn phenomenon

A

hyperglycemia in the morning due to natural hormonal release

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