Coagulation Cascade Exam 3

Question 1

what are platelets

Answer 1

not true cells; irregularly shaped; responsible for clotting

made in bone marrow

Question 2

what is a normal platelet count

Answer 2

150,000-400,000

Question 3

what is thrombocytopenia

Answer 3

low platelet count <100,000

person has a high risk for bleeding

Question 4

describe the platelet function

Answer 4

detect injury –> go to area of injury –> become “sticky” platelets –> activates and changes shape –> aggregate more and stick to one another –> platelet to platelet aderence –> activates clotting

Question 5

what is a clotting cascade

Answer 5

groups of proteins that when activated form a blood clot
activated by tissue injury or infection

EX. I cut my hand and i hold pressure as im holding pressure the system starts to occur; platelets going to the site of injury

Question 6

what is hemostasis

Answer 6

clot plugs the damaged vessel and stops bleeding

Question 7

what is a blood clot

Answer 7

a meshwork of protein strands which stabilize the platelet plug and trap other cells

Question 8

what are protein strands made up of

Answer 8

fibrin

Question 9

what is thrombin

Answer 9

responsible for fibrinogen to fibrin

Question 10

what is anti-thrombin III (AT III)

Answer 10

circulating inhibitor of thrombin (stops the clotting process)

Question 11

what are anticoagulants

Answer 11

inhibit the action or formation of the clotting factors

-PREVENT clots

Question 12

what are antiplatelets

Answer 12

prevent platelet plugs from forming by inhibiting platelet aggregation
-best for preventing heart attacks and stroke