Hormonal Gene regulation: Nuclear receptors-006

Question 1

their functions ?

Answer 1

Question 2

What are Transcription factors ?

Answer 2

Question 3

Answer 3

Question 4

Answer 4

Question 5

Answer 5

Question 6

Mechanism of work of Type I nuclear receptors ?

Answer 6

Question 7

Answer 7

Question 8

Explain

Question 9

Answer 9

Question 10

Answer 10

Question 11

How does ligands of Type IV nuclear receptors bind ?

Answer 11

Question 12

explain

Question 13

Answer 13

Question 14

Answer 14

Question 15

3 types of Transcriptional activities of Nuclear receptors ?

Answer 15

Explain the figure

Question 16

Answer 16

Question 17

Answer 17

Question 18

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Question 19

Answer 19

Question 20

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Question 21

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Question 22

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Question 23

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Question 24

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Question 25

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Question 26

GR dysfunction Associated Diseases ؟

Answer 26

Question 27

ER-α dysfunction Associated Diseases ?

Answer 27

Question 28

Other ER-α dysfunction Associated Diseases ?

Answer 28

Question 29

AR dysfunction associated dsieases ?

Answer 29

Question 30

TRα dysfunction associated diseases ?

Answer 30

TRα dysfunction is assiciated with pituitary adenomas and thyroid cancer.

Question 31

TRβ dysfunction associated diseases ?

Answer 31

TRβ dysfunction is assiciated with generalized resistance to thyroid hormone (RTH) in addition to Grave’s disease, and psychological traits such as low intelligence.

Question 32

RARα dysfunction associated diseases ?

Answer 32

RARα dysfunction is assiciated with a variety of types of cleft palate, as well as with schizophrenia and other psychiatric conditions

Question 33

RARβ dysfunction associated diseases ?

Answer 33

RARβ dysfunction has been shown to be associated with schizophrenia, autism, alcoholism, bipolar disorder and attention deficit hyperactivity disorder.

Question 34

RARγ dysfunction associated diseases ?

Answer 34

RARγ dysfunction has been shown to be associated with schizophrenia and other psychiatric conditions.

Question 35

VDR dysfunction associated diseases ?

Answer 35