Hormonal Gene regulation: Nuclear receptors-006 Flashcards by Moustafa Sharawy | Brainscape

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their functions ?

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What are Transcription factors ?

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Mechanism of work of Type I nuclear receptors ?

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Explain

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How does ligands of Type IV nuclear receptors bind ?

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explain

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3 types of Transcriptional activities of Nuclear receptors ?

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Explain the figure

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GR dysfunction Associated Diseases ؟

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ER-α dysfunction Associated Diseases ?

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Other ER-α dysfunction Associated Diseases ?

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AR dysfunction associated dsieases ?

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TRα dysfunction associated diseases ?

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TRα dysfunction is assiciated with pituitary adenomas and thyroid cancer.

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TRβ dysfunction associated diseases ?

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TRβ dysfunction is assiciated with generalized resistance to thyroid hormone (RTH) in addition to Grave’s disease, and psychological traits such as low intelligence.

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RARα dysfunction associated diseases ?

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RARα dysfunction is assiciated with a variety of types of cleft palate, as well as with schizophrenia and other psychiatric conditions

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RARβ dysfunction associated diseases ?

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RARβ dysfunction has been shown to be associated with schizophrenia, autism, alcoholism, bipolar disorder and attention deficit hyperactivity disorder.

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RARγ dysfunction associated diseases ?

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RARγ dysfunction has been shown to be associated with schizophrenia and other psychiatric conditions.

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VDR dysfunction associated diseases ?

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