ESR [017]: Endocrine Aspects of Obesity Flashcards

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The five risk factors of obesity ?

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• increased blood pressure (> 130/85 mmHg)

• high blood sugar levels (insulin resistance)

• excess fat around the waist

• high triglyceride levels

• low levels of good cholesterol (HDL)

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23
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Mechanism of Inflammation in Obesity ?
And how does it present histologicaly ?

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Insulin resistance:

Due to inhibition of the insulin signaling pathway, either by:

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-inflammatory cytokines, or

-phosphorylation &raquo_space; inhibiting components of the insulin signaling pathway

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…..tissue expresses most of the components of RAS system.

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Adipose

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Explain The renin–angiotensin system (RAS)

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32
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Obesity is linked with alteration of…… secretion and an increased risk of incidence of some types of cancer.

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adipokine

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How may Altered adipokine secretion lead to cancer ?

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