ESR [017]: Endocrine Aspects of Obesity Flashcards
The five risk factors of obesity ?
• increased blood pressure (> 130/85 mmHg)
• high blood sugar levels (insulin resistance)
• excess fat around the waist
• high triglyceride levels
• low levels of good cholesterol (HDL)
Mechanism of Inflammation in Obesity ?
And how does it present histologicaly ?
Insulin resistance:
Due to inhibition of the insulin signaling pathway, either by:
-inflammatory cytokines, or
-phosphorylation »_space; inhibiting components of the insulin signaling pathway
…..tissue expresses most of the components of RAS system.
Adipose
Explain The renin–angiotensin system (RAS)
Obesity is linked with alteration of…… secretion and an increased risk of incidence of some types of cancer.
adipokine
How may Altered adipokine secretion lead to cancer ?