ESR [021] Thyroid disease

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Question 3

Figure illustrates 4 histological variations of Thyroid follicele appearance , define each one

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Question 6

Thyroid tissue

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Question 7

Thyroid tissue ;
Define the symbol and identify the stain used

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Question 8

Thyroid tissue ;
Define the symbol and identify the stain used

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Question 12

what” the thyroid pathology ?

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Question 13

Thyroid microscopy ; describe an diagnose

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Question 14

Multinodular thyroid goiter Gross picture ; describde

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Cross-section of a thyroid gland with multinodular goiter. Secondary changes such as hemorrhage and cystic degeneration can be seen. Some of the nodules (&raquo_space; ) are surrounded by an intact capsule.

Question 15

Pathological Thyroid microscopy ; define the abnormalities and diagnose

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Question 16

Pathological Thyroid microscopy ; define the abnormalities and diagnose

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Question 17

Multinodular goiter Clinical presentation ?

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• Markedly enlarged goiter

• Compression on trachea, esophagus (leading to dysphasia, stridor)

• Hyperfunction of thyroid gland (toxic multinodular goiter) with suppressed TSH +/- elevated free T4 or T3

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Question 20

histological picture of Embryonal adenoma ?

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closely packed cells forming cords or trabeculae

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histological picture of Fetal adenoma ?

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small follicles containing no or little colloid separated by abundant loose connective tissue

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histological picture of Simple adenoma ?

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shows closely packed follicles of normal size

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histological picture of Colloid adenoma ?

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large follicles filled with colloid and lined by flat epithelium

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histological picture of Hürthle cell adenoma ?

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shows large granular cells with abundant eosinophilic cytoplasm arranged in trabecular pattern

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Question 28

Hashimoto’s disease Signs & symptoms

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Question 29

Hashimoto’s thyroiditis is suspected What are the tests needed?

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Question 31

Gross picture indicating thyroid pathology ; describe and diagnose

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Question 32

Thyroid microscopy ; identify symbols and diagnose + descibe

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Question 33

Immunofluorescent of thyroid ; Diagnose

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Question 34

Papillary thyroid carcinoma gender preferance ?

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Women > men (2.5:1)

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Papillary thyroid carcinoma age prevalance ?

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Peak incidence: 30-50y

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genes Associated with Papillary thyroid carcinoma ?

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Question 38

Thyroid microscopy ; identify the charecteristic structure and diagno

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Question 39

What are the characteristic nuclear features seen in the epithelial cells of a papillary carcinoma?

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Question 40

Thyroid microscopy ; identify the charecteristic structure and diagno

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Question 43

Thyroid microscopy ; describe and diagnose the pathology

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Question 46

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Micro-papillary carcinoma

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A thyroid carcinoma With Relatively benign course ?

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Question 48

A thyroid carcinoma Associated with iodine deficiency ?

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Follicular thyroid carcinoma

Question 49

Peak age incidence of Follicular thyroid carcinoma ?

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40-60y

Question 50

How does Follicular thyroid carcinoma present ?

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Presents as enlarging solitary nodule or in the context of MNG

Question 51

Descrive metastatic activity of Follicular thyroid carcinoma

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Spread via bloodstream (metastasis in 50%)

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Survival rate of Follicular thyroid carcinoma ?

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Survival rate about 80% at 10 years, and decreasing according to the stage (50% for stage four)

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Question 55

How to differentiate Follicular carcinoma than follicular adenoma Microscopicaly ?

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Question 56

Follicular carcinoma

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Question 57

Follicular carcinoma

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Question 59

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The ablation is conducted as a follow-up treatment following Thyroidectomy

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Question 62

Medullary Carcinoma Microscopic picture ?

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Question 63

Thyroid microscopy ; describe and diagnose

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Medullary carcinoma : • Malignant cells may be round, polyhedral or spindle shaped • Cells may form follicles, pseudo- papillary pattern or are arranged in sheets • A homogenous pink, amyloid containing stroma is noted • It can be visualized by Congo red stain

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Calcitonin

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above 60y

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Question 68

Thyroid microscopy ; identify symbols and diagnose + descibe

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Question 70

a type of hyroid imaging ; identify it

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Question 71

Explain how Thyroid scintigraphy works

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Question 72

Goal of thyroid Fine needle aspiration (FNA) ?

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• To diagnose thyroid neoplasms suitable for surgical resection • To identify non- neoplastic lesions that may be managed conservatively

Question 73

The cytodiagnosis of thyroid nodules by FNA is complex. WHY?

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a. Overlap of cytologic patterns between neoplastic and nonneoplastic lesions b. Overlap of cytologic features between various neoplasms c. Coexistence of non-neoplastic and neoplastic processes

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Question 76

thyroid microscopy and FNA ; identify the structures and diagnose

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Question 77

thyroid FNA and histology ; describe and diagnose

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Question 78

thyroid FNA ; describe and diagnose

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