HC. 6 - Werkingsmechanismen van systemische therapie Flashcards

1
Q

Wat doen tropoisomerase II remmers?

A

Zorgen voor dubbelstrengs DNA breuk in S-fase

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2
Q

Tropoisomerase I remmers doen wat?

A

Enkelstrengs DNA breuk S-fase

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3
Q

Welke microtubulaire middel?

A

Taxanen

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4
Q

Wat doen taxanen?

A

Remmen polymerasatie van tubline in M-fase

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5
Q

Waar werken cytostatica op?

A

Remmen deling van (tumor)cellen

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6
Q
A
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