Group 9 - Thiamine HCl (Vitamin B1)

Question 1

Thiamine HCl (Vitamin B₁)

Drug Class?

Answer 1

Thiamine HCl (Vitamin B1) Drug Class:

• Vitamin

Question 2

Thiamine HCl (Vitamin B1)

Mechanism of Action (MOA)?

Answer 2

Thiamine HCl (Vitamin B1) MOA:

• Required for carbohydrate metabolism

Question 3

Thiamine HCl (Vitamin B1)

Indications?

Answer 3

Thiamine HCl (Vitamin B1) Indications:

• Alcoholism, delirium tremens
• Coma of unknown origin
• Suspect Wernicke or Korsakoff Syndrome
• Other thiamine deficiency syndromes
• Severe congested heart failure

Question 4

Thiamine HCl (Vitamin B1)

Contraindications?

Answer 4

Thiamine HCl (Vitamin B1) Contraindications:

• Do Not Give Intra-arterial

Question 5

Thiamine HCl (Vitamin B1)

Adverse Reactions?

Answer 5

Thiamine HCl (Vitamin B1) Adverse Reactions:

• Hypotension (rare)
• Nausea and vomiting

Question 6

Thiamine HCl (Vitamin B1)

Adult Dose?

Answer 6

Thiamine HCl (Vitamin B1) Adult Dose:

• 100 mg

Question 7

Thiamine HCl (Vitamin B1)

Pediatric Dose?

Answer 7

Thiamine HCl (Vitamin B1) Pediatric Dose:

• Rarely used

Question 8

Thiamine HCl (Vitamin B1)

Onset of Action?

Answer 8

Thiamine HCl (Vitamin B1) Onset of Action:

• Hours

Question 9

Thiamine HCl (Vitamin B1)

Peak Effects?

Answer 9

Thiamine HCl (Vitamin B1) Peak Effects:

• 3 - 5 days

Question 10

Thiamine HCl (Vitamin B1)

Duration of Action?

Answer 10

Thiamine HCl (Vitamin B1) Duration of Action:

• Unavailable

Question 11

Thiamine HCl (Vitamin B1)

AZ Drug Box Minimum Supply?

Answer 11

Thiamine HCl (Vitamin B1) AZ Drug Box Minimum Supply:

• 100 mg

Question 12

Thiamine HCl (Vitamin B1)

Special Notes?

Answer 12

Thiamine HCl (Vitamin B1) Special Notes:

• In the known alcoholic patient, dextrose should not be administered without first giving thiamine.