Group 1 - Nitroglycerin Flashcards

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1
Q

Nitroglycerin

Drug Class?

A

Nitroglycerin

Drug Class:

  • Vasodilator
  • Antianginal
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2
Q

Nitroglycerin

MOA?

A

Nitroglycerin MOA:

  • Smooth muscle relaxant acting on vascular, uterine, bronchial, and intestinal smooth muscle
  • Decreases preload - reduces workload on the heart by causing blood pooling
  • Decreases afterload - arteriolar vasodilation
  • Coronary vasodilation increases blood flow to myocardium and decreases myocardial O2 demand
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3
Q

Nitroglycerin

Indications?

A

Nitroglycerin Indications:

  • Angina
  • Myocardial infarction
  • Congestive heart failure with pulmonary edema
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4
Q

Nitroglycerin

Contraindications?

A

Nitroglycerin

Contraindications:

  • Hypotension
  • Hypovolemia
  • Increased intracranial pressure
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5
Q

Nitroglycerin

Adverse Reactions?

A

Nitroglycerin

Adverse Reactions:

  • CV: Hypotension, reflex tachycardia, bradycardia
  • Headache
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6
Q

Nitroglycerin

Adult Dose?

A

Nitroglycerin

Adult Dose:

  • 0.4 mg SL (Sublingual) tablet or spray, may repeat up to 3 doses every 5 to 10 minutes as long as systolic BP is greater than 90 mmHg
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7
Q

Nitroglycerin

Pediatric Dose?

A

Nitroglycerin

Pediatric Dose:

  • None
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8
Q

Nitroglycerin

Onset of Action?

A

Nitroglycerin

Onset of Action:

  • Seconds
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9
Q

Nitroglycerin

Peak Effects?

A

Nitroglycerin

Peak Effects:

  • 5 - 10 minutes
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10
Q

Nitroglycerin

AZ Drug Box Minimum Supply?

A

Nitroglycerin

AZ Drug Box Minimum Supply:

  • 1 bottle of tablets, or 1 spray bottle
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