Group 1 - Acetylsalicylic Acid, Aspirin, ASA

Question 1

Acetylsalicylic Acid, Aspirin, ASA

Drug Class?

Answer 1

Acetylsalicylic Acid, Aspirin, ASA

Drug Class:

• Analgesic (pain relief)
• Antipyretic (anti fever)
• Anti-inflammatory

Question 2

Acetylsalicylic Acid, Aspirin, ASA

MOA?

Answer 2

Acetylsalicylic Acid, Aspirin, ASA

MOA:

• Decreased platelet aggregation (clumping), by blocking thromboxane A₂

Question 3

Acetylsalicylic Acid, Aspirin, ASA

Indications and Field Use?

Answer 3

Acetylsalicylic Acid, Aspirin, ASA

Indications and Field Use:

• Chest pain, ECG changes, or other signs/symptoms suggestive of acute myocardial infarction (AMI).
• Unstable angina

Question 4

Acetylsalicylic Acid, Aspirin, ASA

Contraindications?

Answer 4

Acetylsalicylic Acid, Aspirin, ASA

Contraindications:

• Bleeding ulcer, hemorrhagic states, hemophilia
• Known hypersensitivity to salicylates or other non-steroidal anti-inflammatories
• Children and adolescents

Question 5

Acetylsalicylic Acid, Aspirin, ASA

Adverse Reactions?

Answer 5

Acetylsalicylic Acid, Aspirin, ASA

Adverse Reactions:

• Use with caution in patients with a history of asthma. Anaphylactic reactions in sensitive people have occurred.

Question 6

Acetylsalicylic Acid, Aspirin, ASA

Adult Dosage?

Answer 6

Acetylsalicylic Acid, Aspirin, ASA

Adult Dosage:

• 162 - 324 mg PO (2 to 4 pediatric 81 mg chewable tablets)

Question 7

Acetylsalicylic Acid, Aspirin, ASA

Pediatric Doseage?

Answer 7

Acetylsalicylic Acid, Aspirin, ASA

Pediatric Doseage:

• None

Question 8

Acetylsalicylic Acid, Aspirin, ASA

Onset of Action?

Answer 8

Acetylsalicylic Acid, Aspirin, ASA

Onset of Action:

• 20 to 30 minutes

Question 9

Acetylsalicylic Acid, Aspirin, ASA

Peak Effects?

Answer 9

Acetylsalicylic Acid, Aspirin, ASA

Peak Effects:

• 2 hours

Question 10

Acetylsalicylic Acid, Aspirin, ASA

Duration of Action?

Answer 10

Acetylsalicylic Acid, Aspirin, ASA

Duration of Action:

• 4 - 6 hours

Question 11

Acetylsalicylic Acid, Aspirin, ASA

AZ Drug Box Minimum Supply?

Answer 11

Acetylsalicylic Acid, Aspirin, ASA

AZ Drug Box Minimum Supply:

• 324 mg

Question 12

Acetylsalicylic Acid, Aspirin, ASA

Special Notes?

Answer 12

Acetylsalicylic Acid, Aspirin, ASA

Special Notes:

• ASA is heat and light sensitive
• Odor of acetic acid (vinegar-like smell) indicates degradation of product