GI2a Flashcards
What do the Chief cells release?
Pepsinogen
What do the Parietal cells release?
IF and HCl
What do the S cells release?
Secretin
What do the I cells release?
CCK
What is the function of CCK?
Contract the gallbladder and relax the sphincter of Oddie.
What do the D cells release?
Somatostatin
What are 5 causes of ulcers?
a. H. Pylori (60% of stomach, 90% duodenum)
b. NSAIDs
c. Z-E syndrome
d. smoking, EtOH
e. cancer
What is an upper GI bleed?
Bleeding above the Ligament of Trietz.
What is melena? What causes it?
Black, stinky poo. It is cause by an upper GI bleed.
Does a duodenal ulcer feel better or worse after eating? Gastric ulcer?
Duodenal: pain Decreases with meals.
Gastric: pain is Greater with meals.
What is the gene related to Wilson’s? What test indicates Wilson’s? What is the only treatment? Symptoms?
Gene: ATP7B
Test: decrease in ceruloplasm
Treatment: liver transplant, D-penicillamine chelation
Symptoms:
Cellular ballooning is indicative of what?
NAFLD.
Tell me 4 things about Hirschsprung’s?
a. deletion of chromosome 10 of RET proto-oncogene
b. codes for proteins that help nerves
c. only affects colon
d. affects mesenteric ganglia
What is the hemochromatosis triad?
a. cirrhosis
b. bronzing
c. diabetes
What anti-bodies are involved in AIH?
a. ANA
b. ASMA