Gen Path Final - Alcohol Flashcards

1
Q

Out of the 178,000 alcohol-related deaths annually, what % are due to drunk driving?

A

50%

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2
Q

What % of violent crimes involves the perpetrator consuming alcohol?

A

50%

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3
Q

T/F: Divorce rate is higher with alcohol abuse disorder vs those w/o

A

True

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4
Q

T/F: Children of alcohol abusers have increased mortality, self-destructive behaviors, hospitalization due to violence, risk of teenage pregnancy and unemployment

A

True

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5
Q

What are the effects/disabilities of fetal alcohol syndome?

A

Physical
Intellectual
Social

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6
Q

T/F: Alcohol use disorder frequently occurs w/ other mental health disorders and vice versa

A

True

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7
Q

Alcohol is absorbed __________ in the stomach and small intestine and distributed to all tissues of body in direct proportion to blood level

A

unaltered

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8
Q

The amount of alcohol exhaled is ___________ to blood level

A

proportional

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9
Q

Impaired BAC

A

0.04%

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10
Q

Legally drunk BAC

A

0.08% (occurs w/ 3 standard drinks)

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11
Q

Binge drinking levels (in one sitting)

A

Women: 4+
Men: 5+

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12
Q

Heavy drinking levels (in a week)

A

Women: 8+
Men: 15+

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13
Q

What metabolizes alcohol to acetaldehyde?

A

Alcohol dehydrogenase

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14
Q

What decreases NAD+ that is required for normal fatty acid oxidation, so it leads to fatty liver?

A

Production of acetaldehyde

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15
Q

Alcohol competes w/ other drugs for __________ enzymes, which leads to toxicities in the liver

A

p450

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16
Q

What are the acute effects of alcohol?

A

CNS depression
Gastritis/ulceration

17
Q

T/F: Alcohol is a toxic, psychoactive, and dependence-producing substance and has been classified as a Group 1 carcinogen by the International Agency for Research on Cancer decades ago – this is the highest risk group, which also includes asbestos, radiation and tobacco

A

True

18
Q

T/F: Alcohol is a carcinogen

A

True

19
Q

Chronic effects in liver

A

Fatty change
Alcohol hepatitis
Cirrhosis

20
Q

Chronic effects in GI

A

Bleeding
Ulceration
Esophageal varices
Dysbiosis

21
Q

Chronic effects in heart

A

Cardiomyopathy
Arrhythmia
IHD
Hypertension

22
Q

Chronic effects in brain

A

Stroke

23
Q

Alcohol causes thiamine deficiency. What does this cause?

A

Peripheral neuropathy
Cerebral atrophy

24
Q

Chronic effects in pancreas

A

Pancreatitis

25
Q

T/F: Alcohol causes immune dysregulation

A

True

26
Q
A