Gen Path Exam 3 - Lab Tests for Anemia Flashcards
Basic screening test and is one of the most frequently ordered laboratory procedures
CBC
The findings in the this test give valuable diagnostic information about the hematologic and other body systems, prognosis, response to treatment, and recovery
CBC
Consists of a series of blood cell tests that determine their:
* number
* variety
* percentage
* concentrations
* quality
CBC
3 main components of the CBC w/ differential
RBC count + indices
WBC count + differential
Platelet count
What can the normal values for a CBC be affected by?
Age
Sex
Race
Which cells are the largest cellular component of blood?
RBCs
Which red, iron-based protein is found in RBCs?
Hemoglobin
What does hemoglobin bind and transport?
O2
CO2
What does hemoglobin contain?
4 molecules of heme
4 molecules of globin
What does each molecule of heme contain?
1 iron ion
What does each molecule of globin contain?
2 alpha chains
2 beta chains
What is the normal shape of a RBC?
Biconcave disc
What does the biconcave shape of a RBC allow the RBC to do?
Increased SA for O2 and CO2 transfer
Bend/flex when entering small capillaries
What do mature RBCs lack?
Nucleus + most organelles
How long do RBCs live?
120 days
What organ removes RBCs?
Spleen
What do these conditions result in?
Polycythemia
Hemoconcentration (dehydration)
Increased RBC count
Increased hematocrit
Increased hemoglobin
What do these conditions result in?
Anemia
Bone marrow suppression/disease
Decreased RBC count
Decreased hematocrit
Decreased hemoglobin
What do these conditions result in?
Chronic or acute blood loss
Fluid overload
Decreased RBC count
Volume percentage of RBCs in whole blood
Hematocrit
Also known as packed cell volume or erythrocyte volume fraction
Hematocrit
RBC count x mean corpuscular cell volume (MCV) = ?
Hematocrit
What do these conditions result in?
Extreme physical exercise
Increased hematocrit
Increased hemoglobin
What do these conditions result in?
Hemodilution
Acute hemorrhage
Decreased hematocrit
Decreased hemoglobin
Amount of hemoglobin in a given volume of whole blood
Hemoglobin, total/whole blood
What do these conditions result in?
Hyperlipidemia
Increased hemoglobin
A hematocrit of < 20% leads to what?
Heat failure and death
A hematocrit of > 60% is associated with what?
Spontaneous clotting of blood
A hemoglobin value < 5.0 leads to what?
Heart failure and death