Gastrointestinal Tract - Structures + Layers Flashcards
What is another word for the GI tract?
The alimentary canal
List the six structures of the alimentary canal.
Mouth Pharynx Oesophagus Stomach Small intestine Large intestine
List the five accessory organs of the alimentary canal.
Teeth
Tongue
Salivary glands
Liver
Pancreas
List the five functions of the digestive system.
Mechanical breakdown Digestion Secretion Absorption Excretion
What is digestion?
The chemical breakdown of food
What is secreted in the alimentary canal?
4
H2O
Enzymes
Buffers
Acid
What is absorbed in the alimentary canal?
5
Substrates
Ions
Vitamins
Water
Minerals
What is excreted in the alimentary canal?
Waste
How many phases of digestion are there?
Three
What are the three stages of digestion?
Cephalic-phase
Gastric-phase
Intestinal-phase
What is the cephalic-phase of digestion?
• Control of gastrointestinal function by stimuli arising in the head (long reflexes)
What are long reflexes?
Stimuli arising in the head e.g. sight or sound
What is the gastric-phase of digestion?
Control by stimuli arising in the stomach (short reflexes)
What is the intestinal phase of digestion?
Control by stimuli arising in the small intestine (short reflexes)
What is the peritoneum?
A serous membrane encapsulated with peritoneal fluid
What is a serous membrane?
A membrane that lines the cavities in the bodies
How many parts are there to the peritoneum?
Two parts
What are the two parts of the peritoneum?
Outer parietal membrane
Inner visceral membrane
What is the outer parietal membrane?
It lines the inner surface of the body wall
What is the inner visceral membrane?
It covers the organs of the peritoneal cavity (also called the serosa of the GIT)
What is often known as the serosa of the GIT?
The inner visceral membrane covering the organs of the peritoneal cavity
Name a condition of the peritoneum.
Peritonitis
What is peritonitis?
Abnormal accumulation of peritoneal fluid
What conditions is peritonitis associated with?
4
Liver disease/cirrhosis
Renal disease
Heart failure
Infection
What is the characteristic feature of peritonitis?
Abdominal swelling
What are two clinical signs of peritonitis?
Heartburn/indigestion
Back pain
What is a mesentery?
A doubled sheet of sandwiched peritoneum
What is the function of mesenteries?
They form access routes for blood/lymph vessels and nerves
Where are organs of the GIT suspended?
They are suspended within the peritoneal cavity
What is the greater omentum?
Adipose tissue secreting a number of “hormone-like” substances called adipocytokines
What are adipocytokines?
substances that are ‘hormone-like’ secreted by adipose tissue
How many layers are there to the tissues of the GIT?
Four
Name the four tissues of the GIT.
Mucosa
Submucosa
Muscularis Externa
Adventitia / Serosa
What is another name for adventitia?
Serosa
What is the mucosa?
3
The inner lining of the GIT
It includes the epithelium and lamina propria
There are regional differences in the mucosa - e.g. microvilli
What types of tissue are found in the mucosa?
2
Epithelia
Lamina propria
What are enterocytes?
Cells of the intestines
Describe the epithelia of the mucosa.
Simple or stratified depending on region
Describe the lamina propria of the mucosa.
4
Loose irregular connective tissue
Blood/lymph vessels
Nerves
Muscularis mucosa
Where is the muscularis mucosa found?
Just underneath the epithelia
Describe the submucosa.
6
Dense irregular connective tissue
Exocrine glands
Larger blood/lymph vessels
Enterogasterones
Chemoreceptors, stretch receptors, osmoreceptors
Submucosal/intrinsic nerve plexus
What type of connective tissue is found in the submucosa?
Dense irregular connective tissue
What do the exocrine glands in the submucosa secrete?
Buffers and mucus
What are enterogastrones?
Any hormone secreted by the mucosa/submucosa of the duodenum in the lower gastrointestinal tract
What are chemoreceptors?
A sensory cell or organ responsive to chemical stimuli
What are stretch receptors?
A sensory receptor that responds to the stretching of surrounding muscle tissue and so contributes to the coordination of muscle activity
What are osmoreceptors?
2
Cells which are sensitized to osmotic pressure.
Osmotic pressure changes with the concentration of solutes in the body.
What is the submucosal/intrinsic nerve plexus?
2
Chain of interconnected neurons
The main control for GI secretion and local blood flow
Describe the muscularis externa.
4
Transverse (circular) & longitudinal layers of SM
Regional differences
Peristalsis (motility) & segmentation
Myenteric intrinsic nerve plexus
What type of muscle is found in the muscularis externa?
Transverse (circular) and longitudinal layers of smooth muscle
What is the muscularis externa responsible for?
Peristalsis and segmentation
What is segmentation?
Localized contractions of circular muscle of the muscularis layer of the alimentary canal
What is the serosa/adventitia?
5
The outermost layer
Visceral peritoneum
Loose irregular CT covered by simple squamous epithelia
Double layered mesentery, houses vascular and nervous supplies to the GIT
Adventitia at oesophagus
What type of the peritoneum is found in the serosa?
Visceral peritoneum
What type of connective tissue is found in the serosa?
Loose irregular CT
What type of epithelia are found in the serosa?
Simple squamous epithelia
What houses the nervous and vascular supplies for the GIT?
The double layered mesentery of the serosa
In which part of the body is the serosa called the adventitia?
In the oesophagus