Epithelia - Lateral Surface Specialisations Flashcards

1
Q

How are epithelial cell specialised to join together?

A

Epithelial cells have junctional specialisations

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2
Q

What makes up the junctional specialisations of epithelial cells?

A

Cell membrane proteins and lipids

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3
Q

What are the three types of junctional specialisations?

3

A

Tight junctions

Gap junctions

Anchoring junctions

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4
Q

What is another name for tight junctions?

A

Occluding junctions

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5
Q

Where are occluding junctions located?

A

Between two plasma membranes

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6
Q

Write a note on occluding/tight junctions.

3

A

Adhesion belt attaches to terminal web

Prevents passage of water and solutes

Isolates wastes in the lumen

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7
Q

What does a tight junction prevent the passage of?

2

A

Water

Solutes

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8
Q

What does a tight junction do with wastes?

A

They are isolated in the lumen

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9
Q

What does a tight junction isolate in the lumen?

A

Wastes

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10
Q

What is the role of gap junctions?

A

They allow for rapid communication

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11
Q

Write a note on gap junctions

A

They are held together by channel proteins (junctional proteins, connexons)

Allow ions to pass so cells can communicate

Allow the coordination of cilia beating

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12
Q

What hold gap junctions together?

A

Channel proteins

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13
Q

Name two channel proteins that hold together gap junctions.

A

Junctional proteins

Connexons

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14
Q

What passes through gap junctions?

A

Ions

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15
Q

Why do gap junctions allow ions to pass through?

A

So cells can communicate

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16
Q

What are desmosomes composed of?

3

A

Cell adhesion molecules

Dense areas

Intracellular cement

17
Q

How many types of desmosomes are there?

A

Two

18
Q

Name the two types of desmosomes.

A

Spot desmosomes

Hemidesmosomes

19
Q

What are the two roles of spot desmosomes?

A

Tie cells together

Allow bending and twisting

20
Q

What is the role of hemidesmosomes?

A

Attach cells to the basal lamina

21
Q

What is the role of desmosomes?

A

They attach cells together or to extracellular material

22
Q

What is the role of the basal surface?

A

It attaches epithelial cell to extracellular matrix adhesion molecules

23
Q

What is found beneath the basal surface?

A

A network of protein and carbohydrate fibres is found beneath the basal surface

24
Q

What forms the basal membrane?

A

Epithelial cells and underlying connective tissue

25
Q

What is the role of the basal membrane?

A

Separates the epithelium from the underlying connective tissue

26
Q

How may the basal membrane appear?

A

It may be folded

27
Q

What are the two layers of the basal membrane called?

A

Basal lamina

Reticular lamina

28
Q

What are the two layers of the basal lamina called?

A

The lamina lucida

The lamina densa

29
Q

What is the lamina lucida also called?

A

Clear layer

30
Q

What is the lamina densa also called?

A

Dense layer

31
Q

Give three points on the lamina lucida/clear layer.

A

Thin
Secreted by epithelia
Barrier to CT proteins

32
Q

Give three points on the lamina densa/dense layer

A

Thick fibers
Produced by connective tissue
Strength and filtration

33
Q

What produces the lamina lucida/clear layer?

A

They are secreted by epithelia

34
Q

What produces the lamina densa?

A

It is produced by connective tissue

35
Q

Where are stem cells found?

A

Stem cells are found in the basal layer of stratified epithelia

36
Q

What makes up epithelial tissue?

A

Epithelial cells that are attached along their sides