Fundamentals of Histopathology Flashcards
What cells are associated with acute inflammation?
Neutrophils - multi lobed
Lymphoma on a slide is referred to as?
Starry sky appearance - identical cells
Eosinophils are associated with?
Allergic
Parasitic
Tumours e.g. Hodgkins disease
What do eosinophils look like?
Bilobed
Name a condition where eosinophils infiltrate the oesophagus
Asthma of the oesophagus =
Eosinophilic oesophagitis
What cells are seen in urticaria?
Mast cells
What do macrophages look like?
Large cytoplasm
Macrophages are associated with
End of acute inflammation
Chronic inflammation e.g. Granuloma
How do you tell if sputum is from saliva or bronchi?
Presence of neutrophils if from bronchi (can be black if pollution)
How does TB look on histology? What kind of cells are seen on histology?
Granuloma; macrophages
T cells drive secretory nature of macrophages so the cytoplasm grows to accommodate golgi etc
Eputheliod macrophages
Giant cells I.e. Fused macrophages
How does TB look on histology? What kind of cells are seen on histology?
Granuloma; macrophages
T cells drive secretory nature of macrophages so the cytoplasm grows to accommodate golgi etc
Eputheliod macrophages
Giant cells I.e. Fused macrophages
Name an acid fast stain
Ziehl Nelson
Characteristics of SCC
Keratin production
Tight intercellular bridges
Characteristics of adenocarcinomas
Mucin production
Glands
Tumours of glandular epithelium
Where are adenocarcinomas common?
Breast
Lung
Colon
Prostate
What kind of carcinoma is seen in the urinary tract?
Transitional cell carcinoma
Where are SCC found
Dunno
What kind of stain can you do for adenocarcinomas?
Mucin stain
What stain can be done to look for melanin?
Fontana stain
Two types of stains
Histochemical
Immunohistochemical
What are histochemical stains?
A chemical reaction between stain and tissue, causing a recognisable change in colour
Brownness in liver suggests
Iron deposition; haemochromatosis
What stain can you do to check for iron?
Prussian blue stain
What stain is done to look for amyloid?
Congo red stain