Fluid, electrolyte, and acid-base balance Flashcards

1
Q

INTRACELLULAR FLUIDS make up about _____ of the fluid in the body

A

TWO-THIRDS

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2
Q

EXTRACELLULAR FLUIDS make up about ____ of the fluid in the body

A

ONE-THIRD

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3
Q

WAYS THAT FLUID GETS INTO THE BODY

A

INGESTED FLUIDS

INGESTED FOODS

METABOLIC WATER - created by chemical reaction in the body

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4
Q

WHAT ARE SOME WAYS THAT FLUIDS LEAVE THE BODY

A

KIDNEYS

SKIN

LUNGS

GI TRACT

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5
Q

______ is the principle mechanism to regulate fluid intake

A

THIRST

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6
Q

WHERE IS THE THIRST MECHANISM BE CENTERED IN OUR BODY

A

HYPOTHALAMUS

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7
Q

A DECREASE IN BLOOD VOLUME CAUSES ____________

A

A DECREASE IN BLOOD PRESSURE

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8
Q

osmoreceptors (a type of mechanoreceptors) in the hypothalamus detect an increased ratio of solutes to fluid in the blood ( ______ ______ ______ )

A

INCREASED OSMOTIC PRESSURE

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9
Q

our sensation of thirst tends to lag behind our need for water, so it is good to replenish fluids during activities or high temps ____ ____ ____ _____

A

BEFORE you feel thirsty

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10
Q

3 hormones that are key to controlling fluid and solute loss from body

A

ADH - from posterior pit/hypothalamus

ANP - from heart

ALDOSTERONE - from adrenal cortex

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11
Q

ADH is released by the posterior pituitary/hypothalamus in response to

A

an increase in osmotic pressure (decrease in water concentration in body fluids)

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12
Q

ADH stimulates

A

WATER REABSORPTION BY THE KIDNEYS

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13
Q

ANP is released by the heart due to

A

increased blood volume, stretching the atria

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14
Q

ANP stimulates

A

secretion of sodium and chloride by the kidneys, water follows, and blood volume decreases

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15
Q

decreased blood pressure triggers the kidneys to release

A

the enzyme RENIN

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16
Q

renin promotes the conversion of the plasma protein _____ into ____

A

ANGIOTENSINOGEN INTO

ANGIOTENSIN 1

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17
Q

An enzyme in the lungs conveys angiotensin 1 into

A

angiotensin II

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18
Q

angiotensin II stimules

A

the release of ALDOSTERONE from the adrenal cortex

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19
Q

ALDOSTERONE promotes

A

the reabsorption of sodium by the kidneys and the obligatory reabsorption of water

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20
Q

if osmolarity of interstitial fluid increase, such as if the body becomes ______, cells may shrink as fluid leaves cells and moves to interstitial fluid

A

DEHYDRATED

21
Q

if osmolarity of interstitial fluid, on the other hand, decreases, cells may

A

swell as fluids move into cells

***could cause cells to burst

22
Q

SUBSTANCE THAT WHEN DISSOLVED IN WATER DISSOCIATES INTO POSITIVE AND NEGATIVE IONS forming a solution that can conduct an electrical current

A

ELECTROLYTE

23
Q

Most examples of electrolytes can be classified as

24
Q

most abundant electrolyte (90%) extracellular cation (+).

key roles in fluid and electrolyte balance and action potentials in neurons and muscles.

controlled by aldosterone, ADH, and ANP

25
most prevalent anion (-) key roles in fluid and electrolyte balance, part of HCL in the stomach controlled by aldosterone
CHLORIDE
26
Most abundant cation in intracellular fluid fluid electrolyte balance, nerve impulse transmission, muscle contraction, pH controlled by aldosterone
POTASSIUM (K+)
27
second most prevalent extracellular anion (-) fluid, electrolyte, acid-base balance, pH the kidneys either form or excrete it
BICARBONATE (HCO3-)
28
most abundant mineral in the body, with 98% in bones and teeth, 1% in body fluids and other tissues like muscle blood clotting, neurotransmitter release, muscle tone, nerve impulses, muscle contraction levels controlled by several hormones: PTH, calcitriol (vit D), calcitonin (CT)
CALCIUM (Ca++)
29
most esists as part of calcium phosphate salts in bones and teeth. about 15% exists as various ions (H2PO4-, HPO4--, AND PO4---). H2PO4- is the form most often mentioned as an intracellular anion buffer H+, part of ATP, many organic molecules PTH and calcitriol in great part regulate levels
PHOSPHATE
30
much in bones (54%), the rest in intracellular fluids (45%) and extracellular fluids (1%) cofactor in many enzymes needed for metabolism of CHO and PRO, sodium/potassium pump, neuromuscular functioning, synaptic transmission, myocardial fucntion several factors influence secretion by kidneys; hypercalcemia, hypermagnesemia, PTH, and acidosis are among them
MAGNESIUM
31
as electrolytes are often dissolved in body fluids, ELECTROLYTE IMBALANCES OFTEN ACCOMPANY
FLUID IMBALANCE
32
CAUSES OF ELECTROLYTE/FLUID IMBALANCE
excessive perspiration vomiting or diarrhea hormonal problems dietary insufficiency or excess supplementation may also occur due to medications, kidney probs, diabetes, heart failure, cancer, and numerous other conditions
33
electrolyte/fluid imbalances may have MILD TO SEVERE CONSEQUENCES such as
muscle spasms or tenting, fatigue, or cardiac arrhythmias
34
____ is associated with hydrogen ions (H+) and some negative ions
ACIDS
35
____ dissociate in water to hydroxyl ions (OH-) and some positive ions
BASES
36
____ dissociate in water into positive and negative ions, neither of which is hydrogen or hydroxl
SALTS
37
on the pH scale, LOWER NUMBERS ARE ____ ____ while HIGHER NUMBERS ARE ____ ____
STRONG ACIDS; STRONG BASES 7 IS NEUTRAL
38
3 notable MECHANISMS TO MAINTAIN ACID-BASE BALANCE
RENAL REGULATION RESPIRATION BUFFER SYSTEMS
39
KIDNEYS PROVIDE LONG-TERM acid base balance. they can EXCRETE ____ ____ and REABSORB ____ _____
HYDROGEN IONS (H+) BICARBONATE (HCO3-)
40
RESPIRATION is a way to control the acid-base balance, especially in the
SHORT-TERM
41
an increase in CO2 in body fluids increases ______
ACIDITY (lowers pH)
42
BY ELIMINATING CO2 through breathing, we produce less carbonic acid, and less will dissociate into H+ ions, thereby
REDUCING ACIDITY
43
most ____ ____ in the body consist of a weak acid and the salt of that acid, which starts as a weak base
BUFFER SYSTEMS
44
buffers prevent large pH swings by
CONVERTING STRONG ACIDS AND BASES INTO WEAK ONES VERY QUICKLY (milliseconds)
45
inadequate exhalation of CO2 causes blood pH to drop. emphysema, pulmonary edema, brain stem injuries, airway obstruction, and respiratory muscle problems - all can lead to this problem
RESPIRATORY ACIDOSIS
46
loss of HCO3 in body fluids from severe diarrhea, kidney dysfunction, accumulation of an acid (ketosis), and kidney failure to remove H+
METABOLIC ACIDOSIS
47
hyperventilation leads to a loss of CO2 altitude, pulmonary disease, CVA, severe anxiety increasing levels of CO2 can help (bag breathing)
RESPIRATORY ALKALOSIS
48
Loss of acids (vomiting loss of Hal), excessive intake of alkaline meds, diuretics, severe dehydration
METABOLIC ALKALOSIS
49
why are fluid, electrolytes, and acid-base balance often addressed together
IMBALANCES OF ONE TEND TO INVOLVE IMBALANCES IN THE OTHERS