Final exam questions unit 4 Flashcards
Growth hormone deficiency is inadequate growth hormone due to __________ or __________ problem
Hypothalamic, pituitary
Over secretion of growth hormone in childhood is called __________
Pituitary gigantisism
Pituitary gigantisim causes what?
Tall height, large organs, large tongue, blood glucose issues
What is acromegaly?
Excessive growth hormone production
Why is acromegaly in adults instead of gigantisim?
Epiphyseal plate is closed, so only bones and organs enlargen
What causes acromegaly?
Loss of feedback control of GH at hypothalamus or pituitary
or GH secreting tumor
What is the treatment for acromegaly?
GH hormon analog
Hyperthyroidism: excessive production of __________
- what are symptoms?
TH
increased metabolic rate, weight loss, hyperactivity, heat intolerance
What is graves disease?
Autoimmune disorder from formation of antibodies that mimck TSH
What is exothalmos?
Protruding and bulging of eyeballs
Hypothyroidism is what?
decreased production of TH
What are symptoms of hypothyroidism?
Low metabolic rate, lethargy, coldness, weight gain, photophobia
What is destruction of a person’s own immune system called?
Hashimoto thyroiditis
What is goiter?
enlargement of thyroid
What causes goiter?
Dietary iodine deficiency
What is endemic goiter?
What prevelance of goiter in population is a lot
Cushing syndrome is chronic exposure to body’s tissues to excessive levels of __________ hormones
Glucocorticoid
What are symptoms of cushing syndrome?
Body obesity, moon face, buffalo hump, hypertension, excessive hair growth, kidney stones, mentrual irregularities
Addison disease is insufficient production of __________ from adrenal cortex
Steroids (glucocorticoid and mineralocorticoid_
Symptoms of Addison’s disease
Weight loss, fatigue, weakness, hypotension, hyperpigmentation
Adrenogenital syndrome: inability to synthesize __________
Manifests in the __________
Corticosteroids
Embryo
In adrenogenital syndrome, pituitary releases massive amounts of __________
ACTH
Adrenogenital syndrome causes __________ which is what?
Virilization, musculinization
Diabetes Mellitus is what?
in adequate uptake of glucose from blood
What test is done to measure glucose?
Hemoglobin A1C
Type 1 diabetes is what?
Absent production and release of insulin by pancreatic islet cells
What is type 2 diabetes?
decreased insulin release by pancreatic beta cells or decreased insulin effectiveness in peripheral tissues
What is gestational diabetes?
Diabetes in pregnancy women
What is hypoglycemia?
when blood glucose drops below 60 mg/dL
What is anemia?
Mass of erythrocytes is less than normal range
Aplastic anemia is decreased erythrocytes due to defective __________ __________
Red bone marrow
Hemorrhagic anemia is
Immediate blood loss due to chronic ulcers or heavy mentrual flow
Pernicious anemia is chronic progressive anemia in adults caused by body’s failure to absorb vitamin __________
B12
A defect in __________ leads to pernicious anemia
Intrinisc factor
Sickle-cell disease is
Autosomal recessive
Erythrocytes become sickle shaped at lower blood oxygen concentrations
Causes difficulty in flowing through blood vessels
What is leukemia?
Cancer in leukocyte- forming cells
Acute leukemia progresses __________ and occurs in children and young adults
Rapidly
Chronic leukemia progresses __________ occurs in middle-aged and older people
Slowly
Granulocyte leukemia is uncontrolled proliferation of immature cells in __________ __________
- present of __________ numbers of immature granulocye
Myeloid stem cells
Large
Lymphocytic leukemia is increased numbers of malignant __________ or __________ in bone marrow and circulating blood
- involves __________ ad __________
Lymphocytes, lymphoblasts
lymph nodes, spleen
Atherosclerosis is what?
Coronary arteries become narrowed and has plaque
Angina pectoris is what pain?
What is it
Referred
Poorly localized pain in left side of chest
What is myocardial infarction?
Sudden occlusion of coronary artery
- portion of myocardium is deprived of oxygen, some tissue dies
Atrial flutter
Atria beats 200-400 times per minute
Abnormal muscle impulses flow, stimulates atrial muscles and AV node repeatedly
Atrial fibrillation
Impulses are more chatoic than atrial flutter
- irregular heart rate
- ventricles increase and decrease contractions
Premature ventricular vontractions
Stress, caffiene, sleep deprivatoin
- rapid bursts due to abnormal pulses
- initiated within AV node or ventricular conduction system
- not fatal
Ventricular fibrillation
Disorganized, rapid movement of ventricular muscles that replaces normal contraction
- heart does not pump blood, circulation stops
- Leads to cardiac arrets
Varicose veins are __________ veins
Dilated, tortuous (many curves)
In varicose veins, valves become __________, causing blood to pool in one area and vein to swell and budge
Nonfunctional
What is sclerotherapy
Irritant is injected into small varicose veins to make them scar and seal off
What is phlebectomy?
Stripping or removing a vein
Varicose veins in annorectal region is called __________
Hemorrhoids
Deep vein thrombosis is __________ __________ in vein
Blood clot
DVT usually happens in __________ region
Calf, sural