Final: Development of Head/Neck I Flashcards
What is the earliest representation of the facial region?
Stomodeum (oral cavity)
What craniofacial developmental primordia consists of forebrain & midbrain neural crest cells?
Frontonasal prominence
Maxillary & mandibular process are filled with _____ _____ mesenchyme.
Neural crest
_____ _____ are endodermal outpockets from the foregut.
Pharyngeal pouches
_____ _____ are endodermal outpocketings from floor of foregut between pharyngeal arches I & II.
Thyroid diverticulum
_____ _____ are ectodermal inpocketings opposite to associated pharyngeal pouches.
Pharyngeal grooves
_____ _____ are mesenchymal masses between pharyngeal pouches and grooves.
Pharyngeal arches
What connects the ventarl and dorsal aortae?
Aortic arches
What connects the ventarl and dorsal aortae?
Aortic arches
Which Hox gene helps with development of the following areas:
A) Brain/motor nerves
B) Arteries
C) Pharynx/pharyngeal pouches
A) Hoxb-2
B) Hoxb-4
C) Hoxb-5
Development of the first pharyngeal pouch is dependent on _____.
Otx-2
Development of the pharyngeal pouches 3 & 4 are heavily dependent on _____.
Retinoic acid
Development of pharyngeal pouch 2 is somewhat dependent on _____.
Retinoic acid
_____ genes heavily influence dorsoventral patterning of the pharyngeal arches.
Dlx
Edn-1 is used by pharyngeal arch _____ to signal migrating neural crest cells.
One
Cranial ectoderm is prepatterned by _____ signals from pharyngeal endoderm
FGF-8
The frontonasal ectodermal zone is induced by _____ from forebrain.
Shh
division of 1st arch into upper and lower jaw primordia is dependent on _____.
Endothelin-1
T/F: Meckel’s cartilae is derived from neural crest.
True
What do the quadrate and articular bones become and what arch are they derived from?
Quadrate=Incus
Articular=Malleus
Arch 1
What arch is the stapes derived from?
Arch 2
