Exam 4 Study Guide (NO Chapter 16 & 20) Flashcards
all fungi are
chemoheterotrops
fungi tend to grow better at pH of
5
fungi can grow in low ________ content
moisture
fungi are also able to grow in high _____ and _____ concetrations
sugar, salt
fungi are able to resist ________ pressure
osmotic
fungi are able to metabolize complex
carbs
almost all molds are what type of respirator
aerobic
yeasts are what type of respirator
facultative anaerobes
molds and fleshy fungi have a body that is called
thallus
the thallus of molds and fleshy fungi consists of
hyphae filaments
mass of hyphae is called a
mycelium
septate hyphae
contains cross walls
coenocytic hypahe
do not contain septa
vegetative hyphae
obtain nutrients
aerial hyphae are involved with
reproduction
yeasts are non filamentous/filamentous and multicellular/unicellular
non filamentous and unicellular
filamentous fungi can reproduce _________ by fragmentation of their hyphae
asexually
fungi can reproduce sexually and asexually via the formation of
spores
spores involved with reproduction detach from parent and ___________ into a new mold
germinate
two types of reproduction in yeasts
budding and fission
zygomycota
conjugation fungi with coenocytic hyphae; they produce asexual sporangiospores and sexual zygospores (forms when nuclei of two similar cells fuse
microsporidia
obligate intracellular parasites with no mitochondria and sexual reproduction probably occurs in a host (hasn’t been observed)
Ascomycota
sac fungi with septate hyphae. They can be teleomorhic but some are anamorphic. Asexual spores are known as conidiospores, and sexual spores are called ascospores (nuclei that are morphologically similar or dissimilar rise in a saclike ascus)
basidimycota
club fungi with septate hyphae that are formed externally on a base pedestal called a basidium. produced asexually are called conidiophores, produced sexually called basidiospore
teleomorphic
produce sexually and asexually
anamorphic
produce only asexually
define mycorrhizae
symbiotic fungi that help plants to absorb minerals and water through roots
describe the difference between budding yeasts and fission yeasts
budding yeasts divide unevenly while fission yeasts divide evenly
what are dimorphic fungi
refer to fungi that are able to exhibit two forms of growth either yeastlike or mold like, these are temperature dependent and at 37 degrees C they are yeastlike while 25 degree C they are moldlike
teleomorphic fungi
able to produce sexual and asexual spores
Anamorphic fungi
have lost the ability to sexually reproduce and only reproduce asexually
systemic mycoses
occur deep within the body, spores that are typically found in the soil are transmitted through inhalation (first infect the lungs and then spread to other body tissues)
subcutaneous mycoses
occur beneath the skin and are usually acquired by gardeners or farmers (spores or fragments enter through a puncture wound in the skin)
cutaneous mycoses
affect hair, skin and nails
superficial mycoses
localized (hair shafts and superficial epidermal tissue, these are prevalent in tropical climates)
opportunistic mycoses
caused by fungi that are usually harmless in their normal habitat but can become pathogenic in a compromised host
lichen is a mutualistic organism that is a combination of
green algae and fungus
lichen is classified based on the
fungus
in a lichen the alga produces and secretes
carbs
in a lichen the fungus provides
holdfast
in a lichen the _______ protects the ____ from desication
fungus, algae
lichens are characterized by three different morphoglical types
crustose, foliose, fruticose
the thallus of lichens is made of a __________ composed of _________ that grow around algal cells
medulla, hyphae
in a lichen the hyphae projections below the body serve as host fasts that are known as
rhizines
in lichen a protective coating called the ________ covers the algal layer
cortex
lichens seen as food for
herbivores
lichens can survive where
fungi or algae could not survive alone
some significant roles in nature of algae
able to fix CO2 into organic molecules
produce 80% of earths O2
many are symbionts of animals
able to produce algal blooms
brown algae are they multicellular or unicellular
multicellular
what do brown algae have in their cell walls
cellulose and alginic acid
brown algae grow fast or slow
fast
red algae have __________ thalli
branched
red algae are most unicellular or multicellular
multicellular
why can red algae inhabit greater depths of the ocean
they can absorb blue light
red algae can be harvested for
agar, human food (produced by Gracilaria)
green algae are they multi or unicellular
both
green algae contain chlorphyll
a and b
green algae have what in the cell walls
cellulose
green algae store
starch
green algae are thought to give rise to
terrestrial plants
Diatoms are unicellular or
filamentous
Diatoms have what in their cell walls
pectin, silica cell walls
Diatoms are able to store
oil
Diatoms are able to produce
domoic acid
Diatoms domoic acid produce
neurological disease
dinoflagellates also known as
plankton
dinoflagellates are free floating organisms that are unicellular or multicellular
unicellular
dinoflagellates contain what in plasma membrane
cellulose
some dinoflagellates neurotoxins called __________ which clue paralytic shellfish poisoning
saxitoxins
Oomycota also known as _____ molds
water
Oomycota are _____heterotropic with _______ in the cell walls
chemo, cellulose
Oomycota produce
zoospores
oomycota are __________ and ______ __________
decomposer, plant parasites
protozoa are unicellular/multicellular and eukaryotic/prokaryotic
unicellular eukaryotic
protozoa inhabit
soil and water
protozoa feeding and growing form is known as
trophozoite
protozoa asexual reproduction is by
fission, budding, schizogony
protozoa sexual reproduction is by
conjugation
some protozoa produce _____ in order to survive adverse conditions
cysts
protozoa require a large supply of _______
water
protozoa have an outer protective pellicle requiring specialized structures to take in
food
ciliates wave cilia toward moutlike
cytosome
amebae ___________ food
phagocytize
in amebae food is digested in ___________ and wastes eliminated through an anal pore
vacuoles
excavata include those with characteristic
feeding grooves
excavata include
diplomonads, parabasalids, euglenoids
diplomonads
no mitochondria
multiple flagella
parabasalids
undulating membrane
no cyst stage
euglenoids
photoautotrophs/facultative chemotrophs
include: hemoflagellates
hemoflagellate can be transmitted by
bites of blood feeding insects
amebae move by
extending pseudopods
apicomplexa
non motile
obligate intracellular parasites
complex life cycles
ciliates
move by short projections
helminths include
free living and parasitic worms
platyhelminths
flatworms
nematodes
roundoworms
platyhelminths include
trematodes, cestodes
trematodes or flukes
flat and leaf shaped with a ventral and oral sucker
able to absorb food through a cuticle
cestodes also known as
tapeworms
cestodes have a _________ or headscolex
scolex
cestodes scolex have
sucker for attachment
cestodes scolex absorb food through a
cuticle
cestodes contain body segements called
proglottids
cestodes proglottids contain
male and female reproductive organs
Nematoda also known as
roundworms
roundworms are ____________ shape
cylindrical
do roundworms have a complete or incomplete digestive system
complete
roundworms are dioecious which means
the Nematoda contains male spicule for guiding sperm
cellular slime molds resemble
ameba
cellular slime molds ingest
fungi and bacteria
how do cellular slime molds ingest food
phagocytosis
cellular slime mold cells aggregate to form _____ and ______ _____that differentiate into spores
stalks, spore caps
plasmodial slime molds are a mass of __________ with multiple _____
protoplasm, nuclei
plasmodial slime molds are able to move as
giant ameba
what is able to conduct cytoplasmic streaming
plasmodial slime molds
cytoplasmic streaming is when the protoplasm moves and changes ________ and __________ to distribute ________ and _________
speed, directions, oxygen, nuttients
how are parasitic helminths specialized in order to live within their hosts
may lack digestive system
reduced nervous system
reduced or lacking locomotion
complex reproductive system
what is the organism responsible for causing granulomatous amebic encephalitis
balamuthia
fungi hyphae filaments
mycelium, setate, coenocytic
mycelium
mass of hyphae
septate hyphae
contains cross walls
coenocytic hyphae
do not contain cross walls
vegetative hyphae
obtain nutrients
aerial hyphae
involved with reproduction
when do dimorphic fungi grow like yeasts
37 C
when do dimorphic fungi grow like mold
25 C
asexual spores are produced via
mitosis and cell division
2 types of asexual spores
conidospore
sporangiospore
condiospore
not enclosed in a sac
sporangiospore
enclosed in a sac at the end of aerial hypha
sexual spore in the fusion of nuclei from
two opposite mating strains
3 phases of sexual spores
plasmogamy
karyogamy
meisosis
plasmogamy
haploid donor cell nucleus (+) penetrates cytoplasm of recipient cell (-)
karyogamy
+ and - nuclei fuse and form diploid zygote
meiosis
diploid nucleus produces haploid nuclei (sexual spores)
zygomycota
conjugative fungi
coenocytic hyphae
produce asexual and sexual
zygomycota asexual
sporangiospore
zygomycota sexual
zygospore
microsporida
no sexual reproduction is observed but probably occurs in host
no mitochondria or micotubules
obligate intracellular parasites
ascomycota
sac fungi
septate hyphae
telomorphic and anamorphic
sexual and asexual
ascomycota sexual
ascospore
ascomycota asexual
condiospore
basidomycota
form mushrooms
club fungi
septate hyphae
sexual and asexual
basidomycota asexual
condiospores
basidomycota sexual
basidospores
basidospores are formed externally on a base pedestal called
basidum
telomorphs
able to reproduce sexual and asexual
anamorphs
ascomycetes that have lost the ability to reproduce sexually
mycosis
fungal infection
5 types of mycosis
systemic
subcutaneous
cutaneous
superficial
opportunistic
systemic mycoses
deep within body
subcutaneous mycoses
beneath skin
cutaneous mycoses
affect hair, skin and nails
superficial mycoses
localized
opportunistic mycoses
fungi harmless in normal habitat but pathogenic in compromised host
what are some economic effects
bread, wine, hep B, citric acid, cellulase, kills termites
3 ways lichens grow
crustose
foliose
fructose
crustose
encrusted on the substratum
foliose
leaf life
fruticose
finger like
lichen thallus is made of
medulla
rhizine
cortex
lichen medulla
hyphae grown around algal cells
lichen rhizine
hyphae projection below the body
lichen cortex
protective coating over algal layer
lichens are normally the first _______ to colonize newly exposed ____ or ____
lifeforms, soil, rock
lichens secrete _______ acids that chemically weather rock
organic
algae in lichen produce and secrete
carbs
fungus in lichen provides
holdfasts
algae are ____________ that lack roots, stems, leaves of plants
photoautotrophs
algae location depend on
nutrient availability
wavelength of light
surfaces on which they can attach
algae thallus
body of large multicellular algae
holdfasts are for
attachment
all alge reproduce
asexually
what gives dinoflagellates a rigid structure
cellulose in plasma membrane
oomycota are
chemoheterotrophic
protozoa schizogony
multiple fission
dioecious
separate male and female
monoecious
male and female reproductive systems in one animal
life cycle of parasites
egg, larva, adult
humans as definitive hosts
eggs from proglottids are ingested, hatch into larvae and bore into intestinal wall
humans as intermediate hosts
eggs are ingested and hatch in the intestine
larvae migrate to the liver or lungs and develop a hydatid cyst
eggs infective for humans
raccoon roundworm
whipworm
pinworm
larvae infective for humans
heart worm
reemerging infection
arthropods
animals with segmented bodies, hard external skeletons and jointed legs
vectors
arthropods that carry pathogenic microorganisms
arachnida
eight legs
crustacea
four antenae
insecta
six legs
pathology
study of disease
etiology
cause of a disease
infection
invasion/colonization of the body by a pathogen
disease
abnormal state in which the body is not preforming normal functions
when does human microbe begins to establish
utero
how do more microorganism become acquired into the microbe
people, food, pets
normal microbe
permently colonize the host and do not cause disease under normal conditions
transient microbe
may be present for days, weeks, months and then disappear
commensalism
one organism benefits and other is unaffected
mutualism
both organism benefit
parasitism
one organism benefits at the expense of the other
microbial antagonism
competition between microbes
kochs postulates
same pathogen must be present in every case of disease
pathogen must be isolated from the disease host and grown in pure culture
pathogen from pure culture must cause the disease in lab animal
pathogen must be isolated from the inoculated animal and must be shown to be original organism
what are kochs postulates used to prove
cause of infectious disease
exceptions to kochs postulates
some pathogens cause several disease conditions
some pathogens cause disease in only humans
some microbes have never been cultured
incidence is the
number of people who develop a disease during a particular time period
incidence is the indicator of
spread of the disease
prevalence
number of people who develop the disease at a specified time, regardless of when it first appeared
prevalence is the indicator of
how seriously and how long a disease affects a population
what one takes in account old and new cases, prevalence or incidence
prevalence
terms that describe occurrence of a disease
sporadic
endemic
epidemic
pandemic
sporadic
disease that occurs occasionally
endemic
disease that is constantly present in a population
epidemic
disease acquired by many people in a given area in a short time
pandemic
worldwide epidemic
terms describing the severity/duration of a disease
acute
chronic
subacute
latent
acute
symptoms develop rapidly but the disease lasts only a short time
chronic
symptoms develop slowly
subacute
intermediate between acute and chronic
latent
causative agent ins inactive for a long time but then activates and produces symptoms
herd immunity
immunity in most of a population
predisposing factor
makes the body more susceptible to disease
steps to the development of disease
incubation
prodromal
period of illness
period of decline
period of convalescence
incubation
interval between initial infection and first signs and symptoms
prodromal
short period after incubation; early, mild symptoms
period of illness
disease is most severe
period of decline
signs and symptoms subside
period of convalescnce
body returns to its predeceased state
3 reservoirs of infection
human
animal
nonliving
human reservoirs
carriers may have inapparent infections or latent diseases
animal reservoirs
zoonoses are diseases transmitted from animals to humans
nonliving reservoirs
soil and water
3 ways of transmission
contact transmission
vehicle
vector
types of contact transmission
direct contact
congenital transmission
indirect contact transmission
droplet transmission
direct contact transmission
requires close association between the infected and a suseptible host
example of direct contact transmission
kissing
congenital transmission
transmission to mother to fetus or newborn at birth
indirect contact transmissions
spreads to host by a nonliving object called a fomite
example of indirect contact transmission
stethoscopes
droplet transmission
transmission via airborne droplets that travel very short distances
example of droplet transmission
sneezing
vehicle transmission types
airborne
waterborne
foodborne
vector transmission
arthropods, especially fleas, ticks, and mosquitos
2 types of vector transmission
mechanical and biological
mechanical transmission
arthropod carries pathogen on its feet
biological transmission
pathogen reproduces in the vector, transmitted via bites, feces
what vector type is a passive process
mechanical
what vector type is an active process
biological
standard precautions
basic minimum practices
transmitted based precautions
supplemental to standard precautions; designed for known or suspected infections
emerging infectious diseases
diseases that are new, increasing in incidence, or showing a poetical increase in the near future
contributing factors to emerging infectious diseases
genetic recombination
evolution of new strains
widespread use of antibiotics
changes in weather
modern transportation
insect vectors
epidemiology
study of where and when diseases occur and how they are transmitted in populations
epidemiologists
determine etiology of a disease
identify other important factors concerning the spread
develop methods for controlling the disease
assemble data and graphs to outline incidence of a disease
descriptive epidemiology
collection of analysis of data
experimental epidemiology
involves a hypothesis and controlled experiments
clinical trial: test and control group
analytical epidemiology
analyzes a particular disease to determine its probable cause
John snow
mapped the occurrence of cholera in London
what type of epidemiology is this?
descriptive
Ignaz Semmelweis
showed that hand washing decreased the incidence of puerperal sepsis
what type of epidemiology is this
experimental
Florence Nighingale
showed that improved sanitation decreased the incidence of epidemic typhus
what type of epidemiology is this
analytical
pathogenicity
the ability to cause disease by overcoming host defenses
virulence
degree of pathogenicity
examples of portals of entry
mucous membranes
skin
parental route
mucous membranes include the
GI tract
respiratory tract
genitourinary tract
conjuctiva
parental route is when it is deposited directly into tissues when barriers are
penetrated
examples of parental route
bites, cuts, punctures, injections, surgery, splitting of skin
ID50
infectious dose for 50% of a sample population
LD50
lethal dose for 50% of a sample population
what does ID50 measure
virulence of a microbe
what does LD50 measure
potency of a toxin
adherence
process in which almost all pathogens attach to host tissues
adhesions
on the pathogen that bind to receptors on host cells
where could adhesions bind to
glycocalyx
fimbriae
pili
flagella
microbes form biofilms that secrete
glycocalyax
capsules
glycocalax around the cell
why do capsules increase virulence
impair phagocytosis
coagulase
coagulate fibrinogen
kinases
digest fibrin clots
hyaluronidase
digests polysaccharides that hold cells together
collagenase
breaks down collagen
IgA protease
destroy IgA
antigenic variation
pathogens alter their surface antigens and antibodies are rendered ineffective
invasions
surface protein produced by bacteria that rearrange actin filaments of the cytoskeleton
invasions cause membrane
ruffling
biofilm bacteria is more resistant to phagocytosis how?
shielded by extracellular polymeric substance (EPS) of biofilm
microorganism can damage host cells by 4 ways
using hosts nutrients
causing direct damage
producing toxins
induing hypersensitivity
example of microorganism using the host nutrients
siderophores
siderophores
proteins secreted by pathogen that bind iron more tightly than host
ways microorganism cause direct damage
disrupts host cell function
uses host cell nutrients
produces waste products
multiplies in host cells and cause rupture
toxins
poisonous substance produced by microogranisms
toxigenicity
ability of a microorganism to produce a toxin
intotoxications
causes by the presence of a toxin
toxemia
presence of toxin in the hosts blood
exotoxins, protein or lipid
protein
exotoxins are secreted by what type of bacteria
gram pos or neg
exotoxins A-B toxins contain
enzyme component (A)
binding component (B)
are exotoxins soluble in bodily fluids
yes
are exotoxins disease specific
yes
do exotoxins or bacteria produce the specific signs and symptoms of the disease
exotoxins
antitoxins
antibodies against specific exotoxins
toxoids
inactivated exotoxins used in vaccines
genotoxins
damage DNA
membrane disrupting toxins
lyse host cells by disrupting plasma membrane
superantigens
cause an intense immune response due to release of cytokines from host cells
are endotoxins protein or lipid
lipid
endotoxin lipid portion
lipid A
where is lipid A located
LPS of gram neg bacteria
endotoxins do they cause the same signs and symptoms no matter the disease
yes but they don’t all produce effects to same degree
when are endotoxins released
bacterial multiplication or when a gram neg dies
endotoxins stimulate macrophages to release
cytokines
endotoxins cause
DIC or shock
limulus amebocyte lysate is used to test for
endotoxins
limulus amebocyte lysate is the blood of
horseshoe crabs
plasmids
may carry genes for toxins, production of antibiotics, enzymes
lysogenic conversion
changes characteristics of a microbe due to incorporation of a prophage
CPE (cytopathic effects)
visible effects of viral infection on cell
examples of CPE
stopping cell synthesis
using cell lysosomes to release enzyme
fussing cells to create a syncytium
loss of contact inhbititon
alpha and beta protect the host cells __________ cells from viral infection
neighboring
2 ways alpha and beta work to prevent the spread
inhibit synthesis of viral proteins in host cell proteins
kill virus infected host cells by apoptosis
fungi ergot
alkaloid toxins that cause hallucinations
fungi alfatotoxins
carcinogen toxin
mycotoxin
neurotoxins produced by mushrooms
protozoa avoid host defenses by
digesting cells and tissue fluids
growing in phagocytes
antigenic variation
most common portals of exit
respiratory and GI tract
examples of portals of exit of respiratory
coughing and sneezing
examples of portals of exit GI tract
feces and salvia
examples of portals of exit genitourinary tract
urine, secretions from gentials
examples of portals of exit skin infections
drainage from wounds
examples of portals of exit blood
arthropods that bite
needles, syringes